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Pregnancy-related pharmacokinetic changes.

Y Tasnif1, J Morado2, M F Hebert3

  • 1Cooperative Pharmacy Program, University of Texas, Rio Grande Valley TX and Renaissance Transplant Institute, Doctors Hospital at Renaissance, Edinburg, Texas, USA.

Clinical Pharmacology and Therapeutics
|April 16, 2016
PubMed
Summary

Pregnancy significantly alters drug pharmacokinetics by changing distribution, protein binding, and enzyme activity. Renal filtration and drug transporter functions are also modified, impacting how drugs are processed and eliminated.

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