Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Acute Pancreatitis II: Clinical Manifestations and Management01:30

Acute Pancreatitis II: Clinical Manifestations and Management

1.0K
Acute pancreatitis presents a complex medical emergency characterized by rapid onset inflammation of the pancreas, demanding timely diagnosis and management to prevent complications. The condition primarily manifests through severe upper abdominal pain that often radiates to the back. This pain intensifies following the consumption of fatty foods. Accompanying symptoms such as nausea, vomiting, abdominal distention, fever, dyspnea, cyanosis, and jaundice can vary in intensity but significantly...
1.0K
Chronic Pancreatitis II: Collaborative Care01:29

Chronic Pancreatitis II: Collaborative Care

467
The management of chronic pancreatitis is multifaceted, involving a comprehensive approach that includes thorough assessment, diagnostic testing, and a variety of management strategies.
Assessment:
467
Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

5.4K
Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
5.4K
Peptic Ulcer Disease V: Surgical Management and Nursing Care01:25

Peptic Ulcer Disease V: Surgical Management and Nursing Care

1.1K
Surgical management and nursing care are crucial in treating Peptic Ulcer Disease (PUD). Here is an organized and enhanced overview of the surgical interventions and the associated nursing care for PUD:
Surgical Interventions for Peptic Ulcer Disease
1.1K
Acute Pancreatitis I: Introduction01:27

Acute Pancreatitis I: Introduction

1.5K
Pancreatitis is inflammation of the pancreas, an organ located behind the stomach. It can be either acute or chronic.
Acute pancreatitis is characterized by rapid inflammation of the pancreas, often caused by factors like gallstone blockage or excessive alcohol consumption. Chronic pancreatitis, on the other hand, is a slow, progressive inflammation that may result from long-term alcohol abuse, obstructions in the pancreatic duct, or genetic factors.
The causes of acute pancreatitis include:
1.5K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Reasoning in machine vision by learning fast and slow thinking.

Nature communications·2026
Same author

Warm-started reinforcement learning for iterative 3D/2D liver registration.

International journal of computer assisted radiology and surgery·2026
Same author

Real Time Evaluation of Whole Organ Perfusion by Magnetic Resonance Imaging in Ex Vivo Machine-Perfused Liver.

NMR in biomedicine·2026
Same author

Anticoagulation Practice and Risk of Portal Vein Thrombosis Following Pancreaticoduodenectomy or Total Pancreatectomy with Venous Resection: An International Multicentre Cohort Study.

Annals of surgery·2025
Same author

Correction: Deep hashing for global registration of preoperative CT and video images for laparoscopic liver surgery.

International journal of computer assisted radiology and surgery·2025
Same author

Tube2FEM: a general-purpose highly automated pipeline for flow-related processes in (embedded) tubular objects.

Royal Society open science·2025

Related Experiment Video

Updated: Mar 22, 2026

Indocyanine Green-Guided Intraoperative Imaging to Facilitate Video-Assisted Retroperitoneal Debridement for Treating Acute Necrotizing Pancreatitis
04:01

Indocyanine Green-Guided Intraoperative Imaging to Facilitate Video-Assisted Retroperitoneal Debridement for Treating Acute Necrotizing Pancreatitis

Published on: September 8, 2022

3.1K

Interventions for necrotising pancreatitis.

Kurinchi Selvan Gurusamy1, Ajay P Belgaumkar, Adam Haswell

  • 1Department of Surgery, Royal Free Campus, UCL Medical School, Royal Free Hospital, Rowland Hill Street, London, UK, NW3 2PF.

The Cochrane Database of Systematic Reviews
|April 17, 2016
PubMed
Summary
This summary is machine-generated.

The minimally invasive step-up approach for necrotising pancreatitis shows fewer adverse events, less organ failure, and lower costs than open necrosectomy. However, evidence quality is low, and more research is needed.

More Related Videos

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
03:42

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis

Published on: March 15, 2024

1.4K
Application of Indocyanine Green Fluorescence Imaging Technology in Laparoscopic Duodenum-Preserving Pancreatic Head Resection
14:56

Application of Indocyanine Green Fluorescence Imaging Technology in Laparoscopic Duodenum-Preserving Pancreatic Head Resection

Published on: November 21, 2025

291

Related Experiment Videos

Last Updated: Mar 22, 2026

Indocyanine Green-Guided Intraoperative Imaging to Facilitate Video-Assisted Retroperitoneal Debridement for Treating Acute Necrotizing Pancreatitis
04:01

Indocyanine Green-Guided Intraoperative Imaging to Facilitate Video-Assisted Retroperitoneal Debridement for Treating Acute Necrotizing Pancreatitis

Published on: September 8, 2022

3.1K
Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis
03:42

Author Spotlight: Advancements in Retroperitoneal Approach for Necrotizing Pancreatitis

Published on: March 15, 2024

1.4K
Application of Indocyanine Green Fluorescence Imaging Technology in Laparoscopic Duodenum-Preserving Pancreatic Head Resection
14:56

Application of Indocyanine Green Fluorescence Imaging Technology in Laparoscopic Duodenum-Preserving Pancreatic Head Resection

Published on: November 21, 2025

291

Area of Science:

  • Gastroenterology and Hepatology
  • Surgical Gastroenterology
  • Critical Care Medicine

Background:

  • Acute necrotising pancreatitis presents significant mortality and morbidity.
  • Treatment strategies for necrotising pancreatitis lack definitive evidence.
  • High resource utilization is associated with necrotising pancreatitis management.

Purpose of the Study:

  • To evaluate the benefits and harms of various interventions for acute necrotising pancreatitis.
  • To compare open necrosectomy, minimally invasive step-up approaches, and peritoneal lavage.
  • To assess outcomes including mortality, adverse events, organ failure, and costs.

Main Methods:

  • Systematic review and indirect comparison meta-analysis of randomized controlled trials (RCTs).
  • Searched multiple databases up to April 2015 for relevant RCTs.
  • Included 8 RCTs with 306 participants; analyzed 5 trials for main treatments and 3 for variations.

Main Results:

  • Minimally invasive step-up approach demonstrated fewer adverse events, serious adverse events, organ failure, and lower costs compared to open necrosectomy.
  • Endoscopic minimally invasive approach had fewer adverse events but more procedures than video-assisted approach.
  • Evidence quality was low to very low; short-term mortality was 30%; serious adverse events rate was 139 per 100 participants.

Conclusions:

  • Low to very low quality evidence suggests the minimally invasive step-up approach is favorable over open necrosectomy for necrotising pancreatitis.
  • The endoscopic approach may reduce adverse events but increase procedure numbers compared to video-assisted methods.
  • Further research, including the ongoing TENSION trial, is crucial to clarify optimal treatment strategies and outcomes.