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Methodological aspects of a meta-analysis of grass pollen allergen sublingual immunotherapy tablets

Linda S Cox1, Alain Didier2, Pascal Demoly3

  • 1College of Osteopathic Medicine, Nova Southeastern University, Davie, Fla.

The Journal of Allergy and Clinical Immunology
|April 17, 2016
PubMed
Abstract

No abstract available in PubMed .

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Anaphylaxis is a severe, life-threatening hypersensitivity reaction mediated by Immunoglobulin E (IgE) antibodies. When IgE binds to allergens, it triggers the release of mediators– histamine, leukotrienes, and prostaglandins from mast cells and basophils. These mediators cause vasodilation, edema, and inflammation, leading to various symptoms.The primary allergens causing anaphylaxis include food items (e.g., peanuts, shellfish), drugs (e.g., penicillin, asparaginase, corticotropin,...
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