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Cristobalite and Hematite Particles in Human Brain.

Martin Kopani1, A Kopaniova2, M Trnka3

  • 1Institute of Medical Physics, Biophysics, Informatics and Telemedicine, Faculty of Medicine, Comenius University, Sasinkova 2, 811 08, Bratislava, Slovakia. martin.kopani@fmed.uniba.sk.

Biological Trace Element Research
|April 18, 2016
PubMed
Summary
This summary is machine-generated.

Foreign particles like cristobalite and hematite were found in the brain glial cells of Behhet disease patients. These findings suggest long-term accumulation of elements due to environmental factors or metabolic disruption.

Keywords:
Behcet diseaseCristobaliteDiffractionHematiteMetalsParticles

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Area of Science:

  • Neuroscience
  • Materials Science
  • Pathology

Background:

  • Foreign substances can enter the body and accumulate in organs.
  • Behhet disease is a condition affecting various parts of the body.

Purpose of the Study:

  • To identify and characterize foreign particles in the brain glial cells of human patients with Behhet disease.

Main Methods:

  • Scanning electron microscopy (SEM) with energy-dispersive X-ray microanalysis (EDX).
  • Transmission electron microscopy (TEM) with electron diffraction.

Main Results:

  • Irregular micrometer-sized particles with fibrilar or stratified structures were observed.
  • Particles contained elements such as titanium (Ti), iron (Fe), zinc (Zn), and copper (Cu).
  • TEM and diffraction identified the particles as cristobalite and hematite.

Conclusions:

  • The identified particles, cristobalite and hematite, may result from environmental exposure or metabolic changes.
  • The size of the particles indicates long-term accumulation of elements within glial cells.