Related Experiment Video
Updated: Mar 22, 2026

A Three-Dimensional Spheroid Model to Investigate the Tumor-Stromal Interaction in Hepatocellular Carcinoma
Published on: September 30, 2021
Hyponatremia Associated with Hepatocellular Carcinoma
Seong Kwon Ma1, Sung Sun Kim, Eun Hui Bae
1Department of Internal Medicine, Chonnam National University Medical School, Korea.
Hyponatremia, a common electrolyte imbalance, can signal underlying conditions like cancer. This case highlights arginine vasopressin (AVP) expression in liver cancer cells causing hyponatremia.
Area of Science:
- Oncology
- Endocrinology
- Nephrology
Background:
- Hyponatremia is a frequent clinical finding, necessitating a thorough differential diagnosis.
- It is linked to various conditions, including malignancies.
Observation:
- A rare case of hyponatremia associated with hepatocellular carcinoma (HCC) is presented.
- Aberrant expression of arginine vasopressin (AVP) in HCC tumor cells was observed.
Findings:
- Demonstrates a direct link between AVP expression in tumor cells and hyponatremia in HCC.
- This case is one of the few to report AVP abnormal expression in HCC-associated hyponatremia.
Implications:
- Highlights the importance of comprehensive diagnostic work-up for hyponatremia.
- Suggests hyponatremia can serve as an early indicator for underlying disorders, including HCC.
More Related Videos
07:32Author Spotlight: Investigating Immune Cell Dynamics in the Tumor Microenvironment — Challenges and Innovations in Cancer Prognosis
Published on: April 12, 2024
06:38An Oncogenic Hepatocyte-Induced Orthotopic Mouse Model of Hepatocellular Cancer Arising in the Setting of Hepatic Inflammation and Fibrosis
Published on: September 12, 2019
Related Concept Videos
Hemodialysis II: Procedure and Complications
Nephrotic Syndrome I : Introduction
Antihypertensive Drugs: Potassium-Sparing Diuretics
Disorder of Water Balance
Dehydration
Dehydration occurs when the body loses fluids (particularly water).
Causes:
The major causes of dehydration include excessive sweating, fever, vomiting, diarrhea, and diuresis.
Signs and Symptoms:
Symptoms primarily include intense...
Nephrotic Syndrome III : Nursing Management
Regulation of Water Intake