Minimal clinically important difference of the lower-extremity fugl-meyer assessment in chronic-stroke

Shanta Pandian1, Kamal Narayan Arya1, Dharmendra Kumar1

  • 1a Pandit Deendayal Upadhyaya Institute for the Physically Handicapped , New Delhi , India.

Abstract

Insights

The Minimal Clinically Important Difference (MCID) for the Fugl-Meyer assessment: Lower extremity (FMA-LE) in chronic stroke patients is 6. This score indicates a meaningful recovery in lower-extremity function, aiding clinical practice and research.

Area of Science:

  • Rehabilitation Medicine
  • Neuroscience
  • Clinical Motor Assessment

Background:

  • The Minimal Clinically Important Difference (MCID) is crucial for interpreting treatment outcomes in clinical and research settings.
  • The MCID for the Fugl-Meyer assessment: Lower extremity (FMA-LE), a key motor function measure post-stroke, was previously undetermined.

Purpose of the Study:

  • To establish the MCID for the FMA-LE in individuals with chronic hemiparetic stroke using an anchor-based methodology.

Main Methods:

  • A prospective, observational study was conducted involving 65 chronic post-stroke hemiparetic participants (mean duration >16 months).
  • Participants received conventional motor therapy focused on neurophysiological approaches for the affected lower extremity.
  • The FMA-LE was assessed alongside the Functional Ambulation Classification (FAC) and a global rating of patient-perceived changes (GRPPC) to determine MCID.

Main Results:

  • An MCID score of 6 for the FMA-LE was estimated using both the FAC (sensitivity 90%, specificity 94%) and GRPPC (sensitivity 87%, specificity 91%).

Conclusions:

  • A score of 6 on the FMA-LE represents the MCID for chronic post-stroke hemiparetic subjects, signifying a meaningful improvement in lower-extremity function.
  • This established reference value can enhance the interpretation of FMA-LE scores in stroke rehabilitation research and clinical practice.