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Area of Science:

  • Rheumatology
  • Gastroenterology
  • Immunology

Background:

  • Dactylitis is a key feature of spondyloarthropathies.
  • Previous literature reported dactylitis prevalence in enteropathic spondyloarthritis (EASpA) between 2% and 4%.

Purpose of the Study:

  • To determine the prevalence of dactylitis in EASpA patients.
  • To investigate the association of dactylitis with clinical subsets and articular and bowel disease activity.

Main Methods:

  • A study enrolled 78 EASpA patients and 78 controls.
  • Clinical examinations and demographic data were collected.
  • Dactylitis was diagnosed via physical examination and assessed using the Leeds Dactylitis Instrument (LDI).

Main Results:

  • The prevalence of dactylitis in EASpA was 15.38%, predominantly in patients with Crohn's disease and peripheral arthritis.
  • Patients with dactylitis exhibited significantly higher articular and bowel disease activity.
  • A family history of psoriasis predicted dactylitis occurrence, and disease activity correlated with LDI score.

Conclusions:

  • This study revealed a high prevalence of dactylitis in EASpA, exceeding prior estimates.
  • Dactylitis is more common in Crohn's disease patients with peripheral involvement and higher articular activity, suggesting it as a severity marker.
  • The Leeds Dactylitis Instrument (LDI) shows potential as a tool for assessing dactylitis in EASpA.