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Crohn's disease and skin.
A G Gravina1, A Federico1, E Ruocco2
1Department of Clinical and Experimental Medicine 'Magrassi-Lanzara', Gastroenterology Unit, Second University of Naples, Italy.
United European Gastroenterology Journal
|April 19, 2016
Summary
Crohn's disease, an inflammatory bowel condition, can cause skin issues in many patients. This review focuses on these dermatological effects, especially those linked to anti-tumour necrosis factor treatments.
Area of Science:
- Gastroenterology
- Dermatology
- Immunology
Background:
- Crohn's disease is a chronic inflammatory bowel disease affecting the GI tract.
- Extra-intestinal manifestations occur in 6%-40% of patients.
- Skin disorders are common extra-intestinal manifestations of Crohn's disease.
Purpose of the Study:
- To review the spectrum of skin manifestations associated with Crohn's disease.
- To specifically examine skin lesions related to anti-tumour necrosis factor (TNF) therapy.
Main Methods:
- Literature review of studies on Crohn's disease and its skin manifestations.
- Focus on clinical presentations and treatment associations.
Main Results:
- Skin manifestations are frequent in Crohn's disease patients.
- Anti-TNF therapy is associated with specific types of skin lesions.
Conclusions:
- Dermatological conditions are a significant aspect of Crohn's disease management.
- Understanding therapy-associated skin lesions is crucial for patient care.
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