Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Clinical Applications of Epidermal Stem Cells

Clinical Applications of Epidermal Stem Cells

Epidermal stem cells (EpiSCs) are mainly located at the basal layer of the epidermis. These cells repair minor injuries of the skin and replace dead skin cells. However, EpiSCs’ cannot heal severe wounds such as major burns or those from diabetes or hereditary disorders. In such cases, culturing the epidermal stem cells from the patient is possible and has yielded successful treatment options, such as laboratory-grown skin grafts. These grafts are synthesized using a patient’s own...

Burn Injuries

Burn Injuries

Burn injuries occur when the skin and underlying tissues are damaged due to exposure to heat, electricity, chemicals, radiation, or friction. They can vary in severity, from minor superficial burns to severe deep burns that can be life-threatening.
The damage results in the death of skin cells, which can lead to a massive loss of fluid. Dehydration, electrolyte imbalance, and renal and circulatory failure follow, which can be fatal. Burn patients are treated with intravenous fluids to offset...

Staphylococcal Skin Infections

Staphylococcal Skin Infections

Staphylococcus aureus is a Gram-positive coccus that resides harmlessly on the skin and mucous membranes of healthy individuals. When the skin barrier is breached, it can shift from a commensal to an opportunistic pathogen. This transition is facilitated by surface adhesins, such as clumping factor B and S. aureus surface protein G (SasG), which bind to structural proteins, including loricrin and cytokeratin, in the damaged epidermis. Protein A, another key factor, binds the Fc region of...

Aneurysm III: Interprofessional Care

Aneurysm III: Interprofessional Care

Aneurysm management involves either conservative medical therapy or surgical intervention, depending on the size and symptoms of the aneurysm. Conservative management is generally reserved for smaller, asymptomatic aneurysms, while larger or symptomatic aneurysms often necessitate surgical repair.Conservative Medical TherapyFor small, asymptomatic aneurysms, particularly abdominal aortic aneurysms (AAA) less than 5.5 centimeters in diameter, conservative medical therapy is recommended. This...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Room for Leeway: Margin of Safety to Facial Nerve in Retro-Auricular Trans-Meatal Approaches to Mandibular Condyles.

Clinical anatomy (New York, N.Y.)·2026

Same author

High-depth whole genome sequencing of premalignant breast lesions reveals rearrangement hotspots and personalized management opportunities.

Nature communications·2026

Same author

Surgical management of jaw cysts: clinical insights and case report.

British dental journal·2026

Same author

Clinical potential of whole-genome data linked to mortality statistics in patients with breast cancer in the UK: a retrospective analysis.

The Lancet. Oncology·2025

Same author

Consensus statement on the need for a specialist service for paediatric saliva control in neurodevelopmental disabilities.

Archives of disease in childhood·2025

Same author

Oral and maxillofacial surgery (OMFS) 'controlled' second-degree places in the UK - there are sufficient numbers (with high application ratios) to meet current and future OMFS recruitment needs in the UK.

The British journal of oral & maxillofacial surgery·2024

Search research articles

Related Experiment Video

Updated: Mar 22, 2026

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms

Published on: August 11, 2015

A missed scalp laceration causing avoidable sequelae.

Shadi Basyuni¹, Andreana Panayi¹, Valmiki Sharma²

¹Addenbrooke's Hospital, Cambridge, United Kingdom; University of Cambridge, United Kingdom.

International Journal of Surgery Case Reports

|April 19, 2016

Summary

A missed scalp laceration in a polytrauma patient led to complications and extensive treatment. Thorough secondary surveys are crucial to avoid diagnostic errors in severe injury cases.

Keywords:

Infection Laceration Maxillofacial Reconstructive Secondary survey Wound healing

More Related Videos

Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation

Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation

Published on: December 30, 2025

A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity

A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity

Published on: May 7, 2017

Related Experiment Videos

Last Updated: Mar 22, 2026

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms

Minimally Invasive Thumb-sized Pterional Craniotomy for Surgical Clip Ligation of Unruptured Anterior Circulation Aneurysms

Published on: August 11, 2015

Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation

Surgical Approach to Full Soft Tissue Face Allograft Procurement for Vascularized Composite Allotransplantation

Published on: December 30, 2025

A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity

A Large Lateral Craniotomy Procedure for Mesoscale Wide-field Optical Imaging of Brain Activity

Published on: May 7, 2017

Area of Science:

Trauma Surgery
Emergency Medicine
Diagnostic Imaging

Background:

Presents a case of an 81-year-old female with polytrauma after a fall.
An overlooked scalp laceration resulted in significant complications.

Purpose of the Study:

To highlight the importance of thorough secondary surveys in polytrauma patients.
To emphasize the potential for diagnostic errors in complex injury presentations.

Main Methods:

Initial imaging revealed multiple fractures and a cranial hematoma.
Acute anemia prompted a detailed scalp examination, revealing a large laceration.
Infection and necrosis necessitated surgical debridement and closure under general anesthesia.

Main Results:

The missed scalp laceration led to acute anemia requiring blood transfusion.
Infection and necrotic tissue developed, necessitating extensive surgical intervention.
Delayed diagnosis resulted in more complex treatment than if identified early.

Conclusions:

Diagnostic errors are more frequent in patients with multiple or severe injuries.
Thorough wound examination, including adequate cleaning, is vital to identify all injuries.
Effective secondary surveys are essential to prevent complications from overlooked injuries.