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Simultaneous multislice accelerated interleaved EPI DWI using generalized blipped-CAIPI acquisition and 3D K-space
Erpeng Dai1, Xiaodong Ma1, Zhe Zhang1
1Center for Biomedical Imaging Research, Department of Biomedical Engineering, Tsinghua University, Beijing, China.
Magnetic Resonance in Medicine
|April 20, 2016
Summary
This study introduces a new method to accelerate interleaved echo-planar imaging diffusion-weighted imaging (iEPI DWI) using simultaneous multislice (SMS) technology. The technique effectively combines slice unfolding and phase correction, improving imaging efficiency without sacrificing image quality.
Area of Science:
- Magnetic Resonance Imaging
- Diffusion-Weighted Imaging
Background:
- Simultaneous multislice (SMS) accelerates single-shot echo-planar imaging (ssh-EPI) DWI.
- Applying SMS to interleaved echo-planar imaging (iEPI) DWI faces challenges in combining slice unfolding and intershot phase correction.
Purpose of the Study:
- To propose a novel acquisition and reconstruction method for SMS-accelerated high-resolution iEPI DWI.
- To address the obstacles in applying SMS to multishot DWI.
Main Methods:
- Generalized the blipped-controlled aliasing in parallel imaging (blipped-CAIPI) for iEPI.
- Designed an SMS 3D navigator acquisition for intershot phase variations.
- Performed simultaneous slice unfolding and intershot phase correction in a 3D k-space.
Main Results:
- Successfully unfolded simultaneously excited slices.
- Effectively suppressed artifacts from intershot phase variations.
- Achieved improved imaging efficiency with comparable image quality to unaccelerated iEPI DWI.
Conclusions:
- The proposed method effectively accelerates multishot high-resolution DWI.
- This technique may benefit neuroscience research and clinical diagnosis.

