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Liquid-Phase Laser Induced Forward Transfer for Complex Organic Inks and Tissue Engineering.

Alexander K Nguyen1, Roger J Narayan2

  • 1Joint Department of Biomedical Engineering, University of North Carolina, Campus Box 7575, Chapel Hill, NC, 27599-7575, USA.

Annals of Biomedical Engineering
|April 20, 2016
PubMed
Summary

Laser Induced Forward Transfer (LIFT) offers precise, gentle picoliter droplet deposition for microelectronics and tissue engineering. This versatile biotechnology tool efficiently uses low reagent volumes in simple lab settings, enhancing sensor and medical device quality.

Keywords:
Cell printingLaser induced forward transferRegenerative medicineTissue engineering

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Area of Science:

  • Biotechnology
  • Materials Science
  • Microfabrication

Background:

  • Laser Induced Forward Transfer (LIFT) is a novel plotting technique.
  • It offers precise picoliter droplet deposition, surpassing traditional methods like inkjet printing.
  • LIFT is gentle, preserving sensitive materials during transfer.

Purpose of the Study:

  • To explore the capabilities and applications of LIFT technology.
  • To highlight LIFT's advantages in biotechnology, microelectronics, and tissue engineering.
  • To categorize LIFT variants and their specific uses.

Main Methods:

  • Review and categorization of existing LIFT strategies and variants.
  • Analysis of LIFT's mechanism for precise and gentle material deposition.
  • Evaluation of LIFT's performance with diverse materials, from inks to cells.

Main Results:

  • LIFT enables precise deposition of picoliter droplets with high material integrity.
  • The technique is compatible with a wide range of materials and rheological properties.
  • Successful applications demonstrated in microelectronics, sensors, medical devices, and tissue engineering with high cell viability.

Conclusions:

  • LIFT is a versatile and efficient technology for precise material deposition.
  • It offers significant advantages over incumbent technologies, particularly for sensitive biological materials.
  • LIFT shows great promise for advancing fields like regenerative medicine and advanced sensor development.