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Updated: Mar 22, 2026

Isolation and Expansion of Adult Canine Hippocampal Neural Precursors
Published on: November 29, 2016
Engineering of Adult Neurogenesis and Gliogenesis
Benedikt Berninger1, Sebastian Jessberger2
1Adult Neurogenesis and Cellular Reprogramming, Institute of Physiological Chemistry & Focus Program Translational Neuroscience, University Medical Center, Johannes Gutenberg University Mainz, 55128 Mainz, Germany.
Abstract:
Neural stem/progenitor cells (NSPCs) retain their ability to generate newborn neurons throughout life in the mammalian brain. Here, we describe how recently developed virus- and transgenesis-based techniques will help us (1) to understand the functional effects of neurogenesis in health and disease, (2) to design novel approaches to harness the potential for NSPC-associated endogenous repair, and (3) to induce the generation of neurons outside the main neurogenic niches in the adult brain.
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