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Human bocavirus infections among children less than two years old in Iran during fall and winter 2012-2013

Maryam Tabasi1, Talat Mokhtari-Azad1, Mohammad Reza Eshraghian1

  • 1School of Public Health, Tehran University of Medical Sciences.

Iranian Journal of Microbiology
|April 20, 2016
PubMed

Insights

Human bocavirus (HBoV) was detected in 10.7% of young children with respiratory illnesses in Iran. This study identified HBoV1 as the dominant genotype, highlighting its role in pediatric respiratory infections.

Area of Science:

  • Virology
  • Pediatrics
  • Infectious Diseases

Background:

  • Human bocavirus (HBoV) is a recently identified parvovirus.
  • HBoV is frequently detected in children experiencing acute respiratory tract infections.

Purpose of the Study:

  • To determine the prevalence and genotype distribution of HBoV in Iran.
  • To understand the role of HBoV in pediatric respiratory illnesses within the Iranian population.

Main Methods:

  • Conventional PCR was employed to analyze throat swab samples.
  • The study included children under two years old presenting with respiratory illnesses during the fall and winter of 2012-2013.

Main Results:

  • HBoV DNA was identified in 10.7% (15/140) of the samples.
  • Phylogenetic analysis confirmed all detected strains belonged to the HBoV1 genotype.
  • While negative for influenza, two cases showed co-infection with RSV (Respiratory Syncytial Virus).

Conclusions:

  • This research contributes to understanding HBoV's prevalence and genetic diversity in Iran.
  • HBoV1 is a significant cause of acute respiratory infections in young Iranian children.
  • Further research is warranted to fully elucidate HBoV's impact on pediatric respiratory health.
Abstract

Keywords:
Human bocavirusIranchildrengenotype

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