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Updated: Mar 22, 2026

Author Spotlight: High-Throughput Measurement of Intracellular ROS Levels in Hepatocellular Lines
Published on: January 19, 2024
Recent progress in the development of fluorescent, luminescent and colorimetric probes for detection of reactive
Xiaoqiang Chen1, Fang Wang, Ji Young Hyun
1Department of Chemistry and Nano Science, Ewha Womans University, Seoul 03760, Korea. jyoon@ewha.ac.kr.
Abstract:
Reactive oxygen (ROS) and nitrogen (RNS) species cause oxidative and nitrosative stresses, respectively. These stresses are implicated not only in diverse physiological processes but also in various pathological processes, including cancer and neurodegenerative disorders. In addition, some ROS and RNS in the environment are pollutants that threaten human health. As a consequence of these effects, sensitive methods, which can be employed to selectively monitor ROS and RNS in live cells, tissues and organisms as well as in environmental samples, are needed so that their biological roles can be understood and their concentrations in environmental samples can be determined. In this review, fluorescent, luminescent and colorimetric ROS and RNS probes, which have been developed since 2011, are comprehensively discussed.
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