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Updated: Mar 22, 2026

Frailty Assessment in an Aging Mouse Model
Published on: September 23, 2025
Frailty and Cognition
M Houles1, M Canevelli, G Abellan van Kan
1Mathieu Houles, Gérontopôle, Service de gériatrie, CHU PURPAN Toulouse, 170 avenue de Casselardit, 31059 Toulouse cedex 9, France, E-mail : houles.m@chu-toulouse.fr, Fax : +33.5.61.77.25.93, Telephone : +33.5.61.77.66.01.
Abstract:
Frailty is a common, heterogeneous, geriatric syndrome associated with adverse health events. Over the last years, a growing debate has emerged concerning the inclusion of cognitive impairment in the definition of frailty. In fact, cognitive impairment has been increasingly recognized as a potential contributor to the clinical vulnerability of older persons. This review presents key studies describing the interrelationships between cognition and frailty; in particular we examine the clinical relevance of cognitive impairment in the determination of the frailty syndrome.
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