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Immunocytochemistry and Immunohistochemistry

Immunocytochemistry and Immunohistochemistry

Immunocytochemistry (ICC) and immunohistochemistry (IHC) are techniques that use antibodies to check for specific proteins or antigens in a sample. The technique was first published by Albert Coons in 1941 to detect the presence of pneumococcal antigen in tissue sections from mice infected with Pneumococcus. Immunocytochemistry helps localization of proteins or antigens in individual cells like blood cells, stem cells, etc., while immunohistochemistry does the same for tissue samples.
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Related Experiment Video

Updated: Mar 22, 2026

Digital Analysis of Immunostaining of ZW10 Interacting Protein in Human Lung Tissues

Digital Analysis of Immunostaining of ZW10 Interacting Protein in Human Lung Tissues

Published on: May 1, 2019

IHC Optical Density Score: A New Practical Method for Quantitative Immunohistochemistry Image Analysis

Seyed Morteza Seyed Jafari¹, Robert E Hunger

¹Department of Dermatology Inselspital, Bern University Hospital Bern, Switzerland.

Applied Immunohistochemistry & Molecular Morphology : AIMM

|April 20, 2016

Summary

No abstract available in PubMed .

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