Generalized Weakness in a Transplant Patient: A Case Presentation

Generalized weakness in transplant patients is a major complaint in tertiary rehabilitation hospitals. The diagnosis and management of generalized weakness in this population pose challenges for physicians. We present the case of a transplant patient with generalized weakness who was eventually diagnosed with calciphylaxis using a multidisciplinary diagnostic approach of electrodiagnostics, vascular study, and skin biopsy. Calciphylaxis is a rare cutaneous disorder that mimics other collagen vascular diseases in its presentation and fulminant course. Physiatrists should be cognizant of calciphylaxis, as it signals a poor prognosis if not correctly diagnosed and treated in a timely manner, with high incidence of sepsis, wound pain, and disability.

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