Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Brain Imaging01:14

Brain Imaging

898
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
898
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

10.3K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
10.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The mesenteric model of abdominal anatomy.

Nature reviews. Gastroenterology & hepatology·2026
Same author

Subconjunctival administration of allogeneic TNF-α/IL-1β licensed MSCs promotes an anti-inflammatory microenvironment in a murine model of severe alkali burn.

International immunopharmacology·2026
Same author

Making the invisible visible: A global examination of careers and recognition for Imaging Scientists in core facilities.

Journal of microscopy·2026
Same author

Adaptive ER stress promotes mitochondrial remodelling and longevity through PERK-dependent MERCS assembly.

Cell death and differentiation·2025
Same author

Correction: Small extracellular vesicles secreted from TGF-β1-licensed mesenchymal stromal cells reduce inflammation-associated injury following corneal alkali burn.

Stem cell research & therapy·2025
Same author

Understanding the Impact of Reperfusion in the Development of a Safe Compression Therapy.

Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada·2025
Same journal

Autologous collagen-induced chondrogenesis versus mesenchymal stem cell therapy combined with high tibial osteotomy for medial knee osteoarthritis: a retrospective study.

Stem cell research & therapy·2026
Same journal

Role of microRNAs in cisplatin response of cancer stem cells.

Stem cell research & therapy·2026
Same journal

PBAE nanoparticle-mediated delivery of ASCL1 and NGN2 genes for astroglia-to-neuron reprogramming to remodel glial scar for spinal cord injury repair.

Stem cell research & therapy·2026
Same journal

Lipoaspirate-derived secretome restores redox homeostasis to attenuate pathological scar formation.

Stem cell research & therapy·2026
Same journal

Identification and enrichment of human retinal organoid-derived red/green cone-competent precursors with enhanced axon dynamics.

Stem cell research & therapy·2026
Same journal

PTGIS inhibited osteogenic and promoted angiogenic differentiation of bone marrow mesenchymal stem cells via endoplasmic reticulum stress mediated PI3K/AKT signaling.

Stem cell research & therapy·2026
See all related articles

Related Experiment Video

Updated: Mar 22, 2026

Multimodal Imaging of Stem Cell Implantation in the Central Nervous System of Mice
10:25

Multimodal Imaging of Stem Cell Implantation in the Central Nervous System of Mice

Published on: June 13, 2012

11.6K

Functional imaging for regenerative medicine.

Martin Leahy1,2, Kerry Thompson3, Haroon Zafar4

  • 1Tissue Optics & Microcirculation Imaging Group, School of Physics, National University of Ireland (NUI), Galway, Ireland. martin.leahy@nuigalway.ie.

Stem Cell Research & Therapy
|April 21, 2016
PubMed
Summary
This summary is machine-generated.

Selecting appropriate in vivo imaging techniques is crucial for advancing stem cell therapies. This review explores current and future imaging technologies for regenerative medicine, emphasizing label-free methods for smoother clinical translation.

Keywords:
FunctionalImagingLabel-freeMicroscopyOptical coherence tomographyPhotoacoustic imagingStem cells

More Related Videos

Molecular Imaging to Target Transplanted Muscle Progenitor Cells
09:24

Molecular Imaging to Target Transplanted Muscle Progenitor Cells

Published on: March 27, 2013

9.5K
Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

11.0K

Related Experiment Videos

Last Updated: Mar 22, 2026

Multimodal Imaging of Stem Cell Implantation in the Central Nervous System of Mice
10:25

Multimodal Imaging of Stem Cell Implantation in the Central Nervous System of Mice

Published on: June 13, 2012

11.6K
Molecular Imaging to Target Transplanted Muscle Progenitor Cells
09:24

Molecular Imaging to Target Transplanted Muscle Progenitor Cells

Published on: March 27, 2013

9.5K
Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring
17:16

Registered Bioimaging of Nanomaterials for Diagnostic and Therapeutic Monitoring

Published on: December 9, 2010

11.0K

Area of Science:

  • Regenerative Medicine
  • Biomedical Imaging
  • Stem Cell Therapy

Background:

  • In vivo imaging is essential for understanding stem cell therapy function within its natural context.
  • Choosing the right imaging techniques early is critical for successful translation to clinical trials.
  • Imaging can elucidate biological, biochemical, and biomechanical mechanisms of stem cell therapies.

Purpose of the Study:

  • To explore successful imaging techniques in stem cell therapy discovery.
  • To predict optimal imaging technologies for translation and future applications.
  • To highlight the importance of imaging modality selection in regenerative medicine.

Main Methods:

  • Review of existing in vivo and in vitro imaging techniques.
  • Analysis of limitations for in vivo applications, including scattering and depth penetration.
  • Discussion of label-free versus labeled imaging and optical clearing techniques.

Main Results:

  • Microscopies and nanoscopies offer high resolution but are limited to superficial applications in vivo.
  • Scattering in tissues significantly limits imaging depth, though optical clearing can mitigate this.
  • Label-free techniques offer advantages for consistent progression through clinical trials.

Conclusions:

  • Careful consideration of imaging modalities is necessary for successful stem cell therapy progression.
  • Label-free techniques are advantageous for translational research where feasible.
  • Future research should focus on developing advanced imaging solutions for deeper tissue penetration and broader applicability in regenerative medicine.