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Peripheral Templation Generates an M(II) 6 L4 Guest-Binding Capsule.

Felix J Rizzuto1, Wen-Yuan Wu1,2, Tanya K Ronson1

  • 1Department of Chemistry, University of Cambridge, Lensfield Road, Cambridge, CB2 1EW, UK.

Angewandte Chemie (International Ed. in English)
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Summary

Self-assembling pseudo-octahedral capsules were created using metal ions and organic ligands. Tetraphenylborate anions unexpectedly templated the capsule formation externally, enabling subsequent internal guest binding.

Keywords:
host-guest chemistryplatonic solidsself-assemblysupramolecular chemistrytemplation

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Area of Science:

  • Supramolecular Chemistry
  • Coordination Chemistry
  • Materials Science

Background:

  • Pseudo-octahedral M(II)6L4 capsules are formed via subcomponent self-assembly.
  • These capsules involve 2-formylphenanthroline, triamines, and metal ions.
  • Understanding guest binding and templating is crucial for capsule design.

Purpose of the Study:

  • To investigate the self-assembly of M(II)6L4 capsules.
  • To determine the binding modes of various guests, particularly tetraphenylborate anions.
  • To explore the templating effect of peripherally bound guests on capsule formation.

Main Methods:

  • Subcomponent self-assembly using 2-formylphenanthroline, triamines, and M(II) metal ions.
  • Analysis of guest binding within the capsule cavity.
  • Spectroscopic and crystallographic techniques to elucidate binding configurations.

Main Results:

  • Pseudo-octahedral M(II)6L4 capsules were successfully synthesized.
  • Neutral guests and most anions bound internally, but tetraphenylborate anions bound externally.
  • External tetraphenylborate binding templated the formation of the capsule structure.
  • The templated capsule could subsequently bind guests in its central cavity.

Conclusions:

  • Tetraphenylborate anions act as external templates for pseudo-octahedral capsule formation.
  • This peripheral templating mechanism is unusual and effective for creating specific supramolecular structures.
  • The formed capsules exhibit host-guest properties, capable of binding guests internally after templation.