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Updated: Mar 22, 2026

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
Published on: January 31, 2020
UK guideline for the use of HIV Post-Exposure Prophylaxis Following Sexual Exposure, 2015
Fiona Cresswell1, Laura Waters2, Eleanor Briggs3
1Brighton and Sussex University Hospital, UK fiona.cresswell@bsuh.nhs.uk.
Abstract:
We present the updated British Association for Sexual Health and HIV guidelines for HIV post-exposure prophylaxis following sexual exposure (PEPSE). This document includes a review of the current data to support the use of PEPSE, considers how to calculate the risks of infection after a potential exposure, and provides recommendations on when PEPSE should and should not be considered. We also review which medications to use for PEPSE, provide a checklist for initial assessment, and make recommendations for monitoring individuals receiving PEPSE. Special scenarios, cost-effectiveness of PEPSE, and issues relating to service provision are also discussed. Throughout the document, the place of PEPSE within the broader context of other HIV prevention strategies is considered.
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