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Chilblain-like leukaemia cutis
Chi Tran1, Gary McEwen2, Garth Robert Fraga3
1Department of Internal Medicine (Dermatology), University of Kansas School of Medicine, Kansas City, Kansas, USA.
Chilblain, or pernio, is an inflammatory response to cold. Atypical chilblain lesions can signal underlying diseases, like the acute myeloid leukaemia presented in this case study.
Area of Science:
- Dermatology
- Hematology
- Oncology
Background:
- Chilblain (pernio) is an inflammatory condition triggered by cold, damp environments.
- Persistent or unusual chilblain lesions warrant investigation for systemic diseases.
- Leukaemia cutis describes leukaemic cell infiltration of the skin.
Observation:
- A case of acute myeloid leukaemia (AML) is presented.
- The patient exhibited symptoms resembling chilblain.
- These lesions were diagnosed as leukaemia cutis.
Findings:
- This case highlights an unusual presentation of acute myeloid leukaemia.
- Leukaemia cutis can manifest as chilblain-like lesions.
- Early recognition of atypical skin lesions is crucial.
Implications:
- Dermatologists and oncologists should consider leukaemia cutis in patients with atypical chilblain.
- This presentation underscores the importance of a multidisciplinary approach in diagnosing rare conditions.
- Investigating persistent skin lesions can lead to early diagnosis of hematologic malignancies.
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