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Evaluating the effects of vitamin D and vitamin E supplement on premenstrual syndrome: A randomized, double-blind,
Hajar Dadkhah1, Elham Ebrahimi2, Nahid Fathizadeh1
1Nursing and Midwifery Care Research Center, Faculty of Nursing and Midwifery, Isfahan University of Medical Sciences, Isfahan, Iran.
Background:
Premenstrual syndrome (PMS) can cause problems in daily work and relationships.
Materials And Methods:
Eighty-six women were randomly assigned to two intervention groups and one control group. Patients were asked to fill out the PMS Daily Symptoms Record for 2 months, and then the participants were randomly assigned to one of the three study groups. Medical intervention was carried out for 2 months with the participants in each group receiving either a tablet containing 200 mg vitamin D, 100 mg vitamin E, or a placebo each day, respectively. After 2 months, the results of pre- and post-intervention were compared. P < 0.005 was considered significant.
Results:
After the intervention, the mean score of the syndrome significantly decreased in all the three groups (12, 16, and 8 participants had decreased scores in vitamin D, vitamin E, and placebo, respectively). The differences between groups were not significant (P > 0.05).
Conclusions:
Supplemental therapy with vitamins D and E is an effective and affordable treatment for PMS.
