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Evolution of a New Class of VEGFR-2 Inhibitors from Scaffold Morphing and Redesign

Nello Mainolfi1, Rajeshri Karki1, Fang Liu2

  • 1Global Discovery Chemistry, Novartis Institutes for Biomedical Research , 100 Technology Square, Cambridge, Massachusetts 02139, United States.

ACS Medicinal Chemistry Letters
|April 21, 2016
PubMed

Keywords:
KDRVEGFVascular endothelial growth factor receptor 2amino heterocycleshinge bindingscaffold morphing

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