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Heart Valves

Heart Valves

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves.
The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...

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Related Experiment Video

Updated: Mar 22, 2026

A Simplified Model for Heterotopic Heart Valve Transplantation in Rodents

A Simplified Model for Heterotopic Heart Valve Transplantation in Rodents

Published on: September 21, 2021

What's up on sutureless valves.

Giuseppe Santarpino¹, Jurij M Kalisnik, Theodor Fischlein

¹Department of Cardiac Surgery, Klinikum Nürnberg, Paracelsus Medical University, Nuremberg, Germany - g.santarpino@libero.it.

Minerva Cardioangiologica

|April 21, 2016

Summary

This summary is machine-generated.

Sutureless aortic bioprostheses offer a faster, easier surgical aortic valve replacement for high-risk patients. These self-anchoring valves reduce operative time, potentially improving patient outcomes.

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Last Updated: Mar 22, 2026

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Area of Science:

Cardiovascular Surgery
Biomedical Engineering
Interventional Cardiology

Background:

Severe aortic stenosis necessitates aortic valve replacement.
High-risk patients present surgical challenges.
Sutureless bioprostheses aim to simplify and expedite valve implantation.

Purpose of the Study:

To review current literature on sutureless aortic bioprostheses.
To compare the Perceval S and Intuity devices.
To discuss future directions and indications for these devices.

Main Methods:

Systematic review of published studies.
Evaluation of sutureless aortic valve implantation techniques.
Analysis of clinical outcomes associated with sutureless valves.

Main Results:

Sutureless valves are designed for self-anchoring, eliminating the need for sutures.
These devices facilitate quicker implantation, reducing operative and ischemic times.
Improved postoperative outcomes are suggested with sutureless valve use.

Conclusions:

Sutureless aortic bioprostheses represent an advancement for high-risk surgical aortic valve replacement.
The Perceval S and Intuity valves are currently available options.
Further research is needed to define optimal indications and long-term efficacy.