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[Transient hyperphosphatasemia in childhood].
Kinderarztliche Praxis
|January 1, 1989
Summary
Transient hyperphosphatasaemia in infants is a temporary increase in serum alkaline phosphatase not caused by illness. This condition requires no extensive diagnostic measures for affected children.
Area of Science:
- Pediatric Medicine
- Biochemistry
Background:
- Elevated serum alkaline phosphatase (SAP) in infants can indicate underlying pathology.
- Distinguishing pathological causes from benign variations is crucial for appropriate infant care.
Observation:
- Four hospitalized infants presented with a significant, unexplained elevation in SAP.
- This elevation was not associated with any identifiable clinical or paraclinical diseases.
Findings:
- The observed phenomenon was identified as transitory hyperphosphatasaemia.
- Literature review suggests this is a transient, benign condition in infants.
Implications:
- Avoidance of unnecessary and extensive diagnostic workups in infants with similar SAP elevations.
- Recognition of transitory hyperphosphatasaemia can prevent medical interventions and associated costs.