Related Experiment Videos
[Transient hyperphosphatasemia in childhood]
Kinderarztliche Praxis
|January 1, 1989
Insights
Transient hyperphosphatasaemia in infants is a temporary increase in serum alkaline phosphatase not caused by illness. This condition requires no extensive diagnostic measures for affected children.
Area of Science:
- Pediatric Medicine
- Biochemistry
Background:
- Elevated serum alkaline phosphatase (SAP) in infants can indicate underlying pathology.
- Distinguishing pathological causes from benign variations is crucial for appropriate infant care.
Observation:
- Four hospitalized infants presented with a significant, unexplained elevation in SAP.
- This elevation was not associated with any identifiable clinical or paraclinical diseases.
Findings:
- The observed phenomenon was identified as transitory hyperphosphatasaemia.
- Literature review suggests this is a transient, benign condition in infants.
Implications:
- Avoidance of unnecessary and extensive diagnostic workups in infants with similar SAP elevations.
- Recognition of transitory hyperphosphatasaemia can prevent medical interventions and associated costs.
Abstract:
During hospitalisation four infants were found to have a marked increase in serum alkaline phosphatase, which could be attributed neither to clinical nor paraclinical diseases and is considered transitory hyperphosphatasaemia. This phenomenon is briefly discussed on the basis of the literature. The children should be protected from extensive diagnostical measures.