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[Transient hyperphosphatasemia in childhood].

S R Weigert, H Schultze

    Kinderarztliche Praxis
    |January 1, 1989
    PubMed
    Summary
    This summary is machine-generated.

    Transient hyperphosphatasaemia in infants is a temporary increase in serum alkaline phosphatase not caused by illness. This condition requires no extensive diagnostic measures for affected children.

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    Area of Science:

    • Pediatric Medicine
    • Biochemistry

    Background:

    • Elevated serum alkaline phosphatase (SAP) in infants can indicate underlying pathology.
    • Distinguishing pathological causes from benign variations is crucial for appropriate infant care.

    Observation:

    • Four hospitalized infants presented with a significant, unexplained elevation in SAP.
    • This elevation was not associated with any identifiable clinical or paraclinical diseases.

    Findings:

    • The observed phenomenon was identified as transitory hyperphosphatasaemia.
    • Literature review suggests this is a transient, benign condition in infants.

    Implications:

    • Avoidance of unnecessary and extensive diagnostic workups in infants with similar SAP elevations.

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  • Recognition of transitory hyperphosphatasaemia can prevent medical interventions and associated costs.