[Combination therapy of acute intestinal obstruction]

Area of Science:

• Gastroenterology
• Surgical Oncology
• Critical Care Medicine

Context:

• Acute intestinal obstruction presents a significant surgical challenge.
• Benign lesions and malignant rectal tumors are common etiologies.
• Postoperative mortality remains a critical concern.

Purpose:

• To evaluate the outcomes of complex surgical interventions for acute intestinal obstruction.
• To identify the primary causes of mortality following these procedures.
• To assess the efficacy of hemosorption in managing postoperative complications.

Summary:

• This study analyzed 108 patients undergoing surgery for acute intestinal obstruction due to benign or malignant conditions.
• Mortality was 21.2%, with endogenous intoxication and peritonitis being the leading causes of death.
• Hemosorption demonstrated effectiveness in preventing and treating postoperative intoxication.

Impact:

• Highlights the critical role of managing endogenous intoxication in surgical outcomes.
• Suggests hemosorption as a key therapeutic strategy in postoperative care for intestinal obstruction.
• Inconclusive hemosorption response may signal persistent intra-abdominal pathology, guiding further management.