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Evaluating the Immune Response of a Nanoemulsion Adjuvant Vaccine Against Methicillin-Resistant Staphylococcus aureus MRSA Infection
Published on: September 1, 2023
Alumina-encapsulated vaccine formulation with improved thermostability and immunogenicity
Hangyu Zhou1, Guangchuan Wang, Xiao-Feng Li
1Center for Biomaterials and Biopathways, Zhejiang University, Hangzhou 310027, China. rtang@zju.edu.cn.
Abstract:
Developing vaccine formulations with excellent thermostability and immunogenicity remains a great challenge. By in situ encapsulating a live-attenuated strain of human enterovirus 71 (EV71) in alumina, we obtained a robust vaccine formulation named EV71@NanoAlum, which features significantly enhanced thermostability and immunogenicity. This attempt follows a material-based tactic for vaccine improvement.
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