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Mice Can Use Second-Order, Contrast-Modulated Stimuli to Guide Visual Perception.

Zeinab Khastkhodaei1, Ovidiu Jurjut2, Steffen Katzner2

  • 1Werner Reichardt Centre for Integrative Neuroscience, University of Tübingen, Tübingen 72076, Germany, Neuroscience Research Center, Baqiyatallah University of Medical Sciences, Tehran, Iran, and Division of Neurobiology, Department Biology II, LMU Munich, Munich 82151, Germany.

The Journal of Neuroscience : the Official Journal of the Society for Neuroscience
|April 22, 2016
PubMed
Summary

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Mice can use second-order visual stimuli, defined by texture or contrast, to guide perception, though performance is reduced compared to first-order, luminance-defined stimuli. This suggests rudimentary visual feature extraction in mouse V1 and LM areas.

Area of Science:

  • Neuroscience
  • Visual Processing
  • Comparative Cognition

Background:

  • Primate visual systems utilize both luminance and texture/contrast for object boundary detection.
  • The capacity of simpler visual systems, like the mouse's, to use second-order visual information remains largely unexplored.

Purpose of the Study:

  • To investigate whether mice can perceive and process second-order visual stimuli.
  • To examine neural responses in mouse visual areas V1 and LM to second-order stimuli.

Main Methods:

  • Behavioral experiments using first-order (luminance-modulated) and second-order (contrast-modulated) gratings.
  • Electrophysiological recordings in mouse V1 and LM to assess neural selectivity and responsiveness.

Main Results:

Keywords:
LMV1classical conditioningcue-invarianceorientation discriminationorientation tuning

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  • Mice demonstrated a reduced ability to discriminate second-order gratings compared to first-order gratings.
  • Neurons in V1 and LM showed weaker responses and selectivity to second-order stimuli, but maintained similar orientation preferences.
  • Learning transfer from first-order to second-order tasks was observed, albeit with diminished performance.

Conclusions:

  • Mice possess a rudimentary ability to use second-order visual information for perception.
  • These findings illuminate basic feature extraction mechanisms in the mouse visual cortex.
  • This research provides insights into the evolution of visual processing hierarchies.