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Sequential detection of multiple phase transitions in model biological membranes using a red-emitting conjugated
Judith E Houston1, Mario Kraft, Ullrich Scherf
1School of Chemistry, University of Dublin, Trinity College, College Green, Dublin 2, Ireland. raevans@tcd.ie.
Physical Chemistry Chemical Physics : PCCP
|April 22, 2016
Abstract:
The anionic conjugated polyelectrolyte, poly[3-(6-sulfothioatehexyl)thiophene] (P3Anionic), functions as a highly sensitive probe of membrane order, uniquely capable of sequentially detecting the three key phase transitions occurring within model phospholipid bilayers. The observed sensitivity is the result of charge-mediated, selective localisation of P3Anionic within the head-groups of the phospholipid bilayer.
