Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists

Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.

Cognitive Development During Adulthood

Cognitive Development During Adulthood

Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...

Neuroplasticity

Neuroplasticity

Neuroplasticity reflects the brain's remarkable capacity to adapt and evolve, responding dynamically to learning, experiences, or injury by reorganizing its neural circuitry. This reorganization involves creating new neural connections and refining old ones through a series of biological processes that contribute to the brain's lifelong development and adaptability.

Cognitive Learning

Cognitive Learning

Cognitive learning is based on purposive behavior, incidental learning, and insight learning.
E. C. Tolman's theory of purposive behavior emphasizes that much behavior is goal-directed. He argued that to understand behavior, we must look at the entire sequence of actions leading to a goal. For instance, high school students study hard, not just due to past reinforcement but also to achieve the goal of getting into a good college.
Tolman introduced the idea that behavior is influenced by...

Alzheimer's Disease: Treatment

Alzheimer's Disease: Treatment

Alzheimer's Disease (AD), a neurodegenerative disorder, is pathologically identified by amyloid plaques and neurofibrillary tangles composed of tau protein. AD pharmacotherapy aims to manage cognitive symptoms, delay disease progression, and treat behavioral symptoms. The treatment is primarily symptomatic and palliative, with no definitive disease-modifying therapy available. Cholinesterase inhibitors, including donepezil (Aricept), rivastigmine (Exelon), and galantamine (Razadyne), are...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Modeled Long-Term Effects of Psilocybin on Dynamic Activity and Effective Connectivity of Fronto-Striatal-Thalamic Circuits.

Human brain mapping·2026

Same author

TTP protects against 6-OHDA-induced dopaminergic neurodegeneration via astrocytic Nrf2/HO-1 activation in cellular and rat models of Parkinson's disease.

Metabolic brain disease·2026

Same author

Personalized machine learning guided intervention for optimizing lifestyle behaviors in depression: a pilot study.

NPP - digital psychiatry and neuroscience·2026

Same author

Climate Cognition Crisis: Urgent Call to Address Air Pollution and Extreme Heat Impacts in Learning Environments of Children in South and Southeast Asia.

The Malaysian journal of medical sciences : MJMS·2026

Same author

Mood and Age Predict Cognitive Complaints in Memory Clinic Patients: A Machine-Learning and Linear Modeling Approach.

European journal of neurology·2026

Same author

Clinical Characteristics of Emergency Visits Related to Recreational Psychedelic Use.

Community mental health journal·2026

Same journal

Dynamic coordination and segregation mechanisms in higher cortex for parallel task processing.

Neuron·2026

Same journal

Higher-order thalamic bursts are drivers of attention control.

Neuron·2026

Same journal

Composing trajectories for rapid inference of navigational goals.

Neuron·2026

Same journal

Peri-head distance coding in the mouse brainstem.

Neuron·2026

Same journal

A two-timepoint framework for sensitive and specific single-cell activity screening.

Neuron·2026

Same journal

From first impressions to bonds: The neural dynamics of social relationships.

Neuron·2026

See all related articles

Search research articles

Related Experiment Video

Updated: Mar 22, 2026

Combining Computer Game-Based Behavioural Experiments With High-Density EEG and Infrared Gaze Tracking

Combining Computer Game-Based Behavioural Experiments With High-Density EEG and Infrared Gaze Tracking

Published on: December 16, 2010

Video Games for Neuro-Cognitive Optimization.

Jyoti Mishra¹, Joaquin A Anguera¹, Adam Gazzaley²

¹Departments of Neurology and Psychiatry, University of California, San Francisco, San Francisco, CA 00000, USA.

|April 22, 2016

Summary

This summary is machine-generated.

Sophisticated video games merge cognitive training with biosensing and neurostimulation for enhanced cognitive performance. Rigorous scientific validation is crucial for advancing this technology in health and disease applications.

Keywords:

closed loop cognitive training multimodal neurofeedback neuroplasticity neurostimulation personalized video game

More Related Videos

Transcranial Direct Current Stimulation for Online Gamers

Transcranial Direct Current Stimulation for Online Gamers

Published on: November 9, 2019

Stereoacuity Improvement using Random-Dot Video Games

Stereoacuity Improvement using Random-Dot Video Games

Published on: January 14, 2020

Related Experiment Videos

Last Updated: Mar 22, 2026

Combining Computer Game-Based Behavioural Experiments With High-Density EEG and Infrared Gaze Tracking

Combining Computer Game-Based Behavioural Experiments With High-Density EEG and Infrared Gaze Tracking

Published on: December 16, 2010

Transcranial Direct Current Stimulation for Online Gamers

Transcranial Direct Current Stimulation for Online Gamers

Published on: November 9, 2019

Stereoacuity Improvement using Random-Dot Video Games

Stereoacuity Improvement using Random-Dot Video Games

Published on: January 14, 2020

Area of Science:

Neuroscience
Cognitive Science
Human-Computer Interaction

Background:

Video games offer engaging platforms for cognitive enhancement.
Real-time biosensing and neurostimulation technologies are advancing rapidly.
Integrating these technologies holds potential for optimizing brain function.

Purpose of the Study:

To explore the potential of integrated video game systems for cognitive optimization.
To highlight the necessity of scientific validation for such technologies.
To discuss opportunities in academic and industry research.

Main Methods:

Conceptual framework integrating cognitive training, biosensing, and neurostimulation.
Literature review of existing technologies and validation studies.
Discussion of research and development pathways.

Main Results:

Integrated systems show promise for enhancing cognitive performance.
A gap exists between technological development and rigorous scientific validation.
Significant academic and industry opportunities are identified.

Conclusions:

Sophisticated video games with integrated biosensing and neurostimulation can optimize cognitive function.
Technological advancement must be accompanied by robust scientific validation.
Collaboration between academia and industry is key to realizing this potential.