[Paraneoplastic syndrome in kidney cancer]

In a prospective study 60 patients suffering from histologically confirmed renal cell carcinoma were examined on paraneoplastic alterations. The following parameters were determined: Stauffer-syndrome (BSG, total protein with serum electrophoresis, alcaline phosphatase, gamma-GT, Quick values), total and ionized calcium, parathormone, calcitonin, hemoglobin, thrombocytes, LDH, IgE and arterial blood pressure. Compared to the findings obtained by other authors, we saw paraneoplastic syndromes only rarely. There was no correlation found to the stage of the tumor or to prognosis. In only four out of 60 patients paraneoplastic led to the diagnosis "renal carcinoma". With the exception of BGS, which was raised in 75% of the patients, paraneoplastic parameters are not suitable for the screening or the early diagnosis of renal carcinomas.