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Updated: Mar 22, 2026

Single-Cell Optical Action Potential Measurement in Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes
Published on: December 22, 2020
A smart switchable module for the detection of multiple ions via turn-on dual-optical readout and their cell imaging
Abhishek Rai1, Alok Kumar Singh2, Avinash Kumar Sonkar1
1Department of Chemistry, Banaras Hindu University, Varanasi, India.
Abstract:
A module switchable as a function of multi-stimuli response has been designed. The module displays sequential logic gate-based detection of multiple ions (Fe(3+), Hg(2+), CN(-) and S(2-)) at ppm levels via a "turn on" signature which potentially meets real-world-challenges through a simple synthetic route, a fast response, water based-activity, naked-eye visualization, regenerative-action, high selectivity and multiple readout for precise analysis. Living cell imaging of Fe(3+) and Hg(2+) has also been carried out in HeLa cell lines.

