Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Sutures of the Skull01:22

Sutures of the Skull

14.1K
The human skull is composed of several bones that come together to protect the brain and support the structures of the face. The junctions where these bones meet are called sutures.
Sutures are immobile joints between adjacent bones of the skull. The narrow gap between the bones is filled with dense, fibrous connective tissue that unites the bones. The long sutures located between the skull bones are not straight but instead follow irregular, tightly twisting paths. These twisting lines tightly...
14.1K
Imaging Studies I: CT and MRI01:14

Imaging Studies I: CT and MRI

1.1K
Introduction: MRI and CT scans are crucial advancements in medical imaging techniques, playing a vital role in diagnosing conditions related to the gastrointestinal (GI) system. Each scan serves distinct purposes, targets specific areas, and requires unique nursing duties.
Description of the Procedures
Computed Tomography (CT) scan:
Computed Tomography (CT) scans use X-ray technology to generate detailed images of bones, organs, and tissues. During the scan, the patient lies on a moving table...
1.1K
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

11.3K
The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle...
11.3K
Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

10.3K
Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
10.3K
Fetal Circulation01:14

Fetal Circulation

4.3K
Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
4.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Comprehensive Structural MRI Phenotyping in <i>Oligophrenin 1-</i>Related Disorder Reveals Characteristic Brain Malformations.

AJNR. American journal of neuroradiology·2026
Same author

Normative modeling for quantitative brain MRI phenotyping and biomarker discovery for pediatric leukodystrophies.

medRxiv : the preprint server for health sciences·2026
Same author

Stratification of Phenotypes in Childhood-Onset <i>COL4A1/COL4A2</i>-Related Disorders Based on Age of Presentation.

Neurology. Genetics·2026
Same author

Comment: The fetal taenia-tela choroidea complex is frequently detectable on MRI when it is needed in the differential diagnosis of posterior fossa abnormalities.

Pediatric radiology·2026
Same author

Recommendations for structural magnetic resonance imaging in infants with first afebrile seizure or new onset epilepsy: Evidence-based recommendations from the ILAE Neuroimaging Task Force.

Epilepsia·2026
Same author

Deep Intronic SVA_E Insertion Identified as the Most Common Pathogenic Variant Associated With Canavan Disease: A Diagnostic Blind Spot.

Neurology. Genetics·2025

Related Experiment Video

Updated: Mar 22, 2026

Grossing of Non-neoplastic Globes, Including Fetal Eyes
05:15

Grossing of Non-neoplastic Globes, Including Fetal Eyes

Published on: May 30, 2025

676

Normal Developmental Globe Morphology on Fetal MR Imaging.

M T Whitehead1, G Vezina2

  • 1From the Department of Radiology, Children's National Medical Center, Washington, DC. MWhitehe@childrensnational.org.

AJNR. American Journal of Neuroradiology
|April 23, 2016
PubMed
Summary
This summary is machine-generated.

Fetal eye development shows age-dependent changes in globe shape. Non-elliptic globes are normal until 29 weeks gestation, after which they become elliptic, aiding in distinguishing normal development from pathology.

More Related Videos

State of the Art Cranial Ultrasound Imaging in Neonates
10:02

State of the Art Cranial Ultrasound Imaging in Neonates

Published on: February 2, 2015

26.5K
Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation
06:56

Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation

Published on: January 7, 2021

2.9K

Related Experiment Videos

Last Updated: Mar 22, 2026

Grossing of Non-neoplastic Globes, Including Fetal Eyes
05:15

Grossing of Non-neoplastic Globes, Including Fetal Eyes

Published on: May 30, 2025

676
State of the Art Cranial Ultrasound Imaging in Neonates
10:02

State of the Art Cranial Ultrasound Imaging in Neonates

Published on: February 2, 2015

26.5K
Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation
06:56

Human Fetal Blood Flow Quantification with Magnetic Resonance Imaging and Motion Compensation

Published on: January 7, 2021

2.9K

Area of Science:

  • Fetal imaging and developmental biology.
  • Ophthalmology and radiology.
  • Human embryology and anatomy.

Background:

  • Fetal globe morphology undergoes age-dependent structural changes during gestation.
  • Early gestation features conical globes with bulging posterolateral margins.
  • Later gestation shows a transition to ellipsoid globe shapes.

Purpose of the Study:

  • To establish normal developmental fetal globe morphology.
  • To define age-specific criteria for fetal globe shape.
  • To differentiate normal fetal eye development from potential abnormalities.

Main Methods:

  • Retrospective analysis of fetal MRI scans from an academic children's hospital.
  • Inclusion criteria: 17-39 weeks gestation, exclusion of malformations and artifacts.
  • Evaluation of globe shape (elliptic/nonelliptic) and hyaloid visibility by two neuroradiologists.

Main Results:

  • Age strongly predicts globe shape (AUC=0.99) and hyaloid visibility (AUC=0.94).
  • Non-elliptic globes are typical up to 22 weeks; elliptic shapes dominate after 29 weeks.
  • Hyaloid vasculature is visible up to 19 weeks, gradually disappearing by 25 weeks.

Conclusions:

  • Nonspheric fetal globe shapes are physiologically normal until 29 weeks gestation.
  • Elliptic globe shapes are characteristic of fetuses at 29 weeks and older.
  • These developmental changes correlate with the resolution of the primary vitreous.