Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Neural Circuits01:25

Neural Circuits

3.2K
Neural circuits and neuronal pools are two of the main structures found in the nervous system. Neural circuits are networks of neurons that work together to carry out a specific task or process. They consist of interconnected neurons and glial cells, which provide structural and metabolic support.
Neuronal pools are collections of nerve cells with similar functions and interact through chemical and electrical signals. These pools include both interneurons (the central neural circuit nodes that...
3.2K
Neuron Structure01:31

Neuron Structure

235.8K
Overview
235.8K
Neuron Structure01:30

Neuron Structure

21.1K
Neurons are the main type of cell in the nervous system that generate and transmit electrochemical signals. They primarily communicate with each other using neurotransmitters at specific junctions called synapses. Neurons come in many shapes that often relate to their function, but most share three main structures: an axon and dendrites that extend out from a cell body.
Structure and Function of Neurons
The neuronal cell body—the soma— houses the nucleus and organelles vital to...
21.1K
Organization of the Brain01:30

Organization of the Brain

3.3K
The brain is an integral component of the nervous system and serves as the center for processing sensory inputs, making decisions, and directing bodily actions. This complex organ is organized into three primary sections: the hindbrain, midbrain, and forebrain, each responsible for a range of vital functions.
Hindbrain
The hindbrain, located at the base of the brain, plays a vital role in regulating automatic processes that sustain life. It includes the medulla oblongata, which is essential for...
3.3K
Somatosensory, Motor, and Association Cortex01:23

Somatosensory, Motor, and Association Cortex

3.9K
The somatosensory cortex in the parietal lobes is crucial for interpreting sensory data such as touch, temperature, and proprioception. The somatosensory cortex, situated in the parietal lobes, plays a vital role in interpreting sensory information like touch, temperature, and proprioception—awareness of body position. This specialized brain region features an organized structure wherein neurons at the top primarily process sensations originating from the lower body. In contrast, those at...
3.9K
Neuronal Communication01:28

Neuronal Communication

4.6K
Neurons, the fundamental units of the brain and nervous system, communicate through complex electrochemical signals that underpin all cognitive and bodily functions. This communication is primarily facilitated by a process involving the generation and propagation of an action potential along the axon of the neuron. When the internal electrical charge of a neuron surpasses a certain threshold, an action potential is triggered. This rapid change in voltage travels swiftly along the axon to the...
4.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Neuromorphic hierarchical modular reservoirs.

Nature communications·2026
Same author

Replicability of multivariate brain-behaviour associations depends on clinical profile.

Communications biology·2026
Same author

Young and old adult brains experience opposite effects of acute sleep restriction on the functional connectivity network.

Imaging neuroscience (Cambridge, Mass.)·2026
Same author

Aging and metabolism contribute separately to brain-body health.

PLoS biology·2026
Same author

Symptom Dimension-Specific Neurotransmitter Correlates of Psychopathology and Cognition in Early Psychosis.

bioRxiv : the preprint server for biology·2026
Same author

Linking human brain functional connectivity to underlying neurotransmission.

bioRxiv : the preprint server for biology·2026
Same journal

Differentiation of cortical areas: effects of free energy minimization with broken symmetry.

Cerebral cortex (New York, N.Y. : 1991)·2026
Same journal

Prior exposure to speech rapidly modulates cortical processing of high-level linguistic structure.

Cerebral cortex (New York, N.Y. : 1991)·2026
Same journal

Beta bursts in SMA mediate anticipatory muscle inhibition.

Cerebral cortex (New York, N.Y. : 1991)·2026
Same journal

Cognitive load modulates the effects of social contexts on facial expression processing.

Cerebral cortex (New York, N.Y. : 1991)·2026
Same journal

The neural mechanisms of aligning spatial perspectives.

Cerebral cortex (New York, N.Y. : 1991)·2026
Same journal

Relationships between bilateral tapping skills and brain gray matter volumes: a voxel-based morphometry study.

Cerebral cortex (New York, N.Y. : 1991)·2026
See all related articles

Related Experiment Video

Updated: Mar 22, 2026

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex
09:55

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex

Published on: September 5, 2018

9.0K

Network-Level Structure-Function Relationships in Human Neocortex.

Bratislav Mišić1, Richard F Betzel2, Marcel A de Reus3

  • 1McConnel Brain Imaging Centre, Montreal Neurological Institute, McGill University, Montréal, QC, H3A 2B4, Canada Department of Psychological and Brain Sciences.

Cerebral Cortex (New York, N.Y. : 1991)
|April 23, 2016
PubMed
Summary
This summary is machine-generated.

Brain functional networks emerge from anatomical connectivity in complex ways. Functional relationships often arise from distributed, non-overlapping structural connections, especially between high-degree hubs.

Keywords:
connectomemultivariatenetworkpartial least squares

More Related Videos

Electrophysiological and Morphological Characterization of Neuronal Microcircuits in Acute Brain Slices Using Paired Patch-Clamp Recordings
10:24

Electrophysiological and Morphological Characterization of Neuronal Microcircuits in Acute Brain Slices Using Paired Patch-Clamp Recordings

Published on: January 10, 2015

18.0K
Microdissection of Mouse Brain into Functionally and Anatomically Different Regions
08:06

Microdissection of Mouse Brain into Functionally and Anatomically Different Regions

Published on: February 15, 2021

58.0K

Related Experiment Videos

Last Updated: Mar 22, 2026

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex
09:55

Large-scale Three-dimensional Imaging of Cellular Organization in the Mouse Neocortex

Published on: September 5, 2018

9.0K
Electrophysiological and Morphological Characterization of Neuronal Microcircuits in Acute Brain Slices Using Paired Patch-Clamp Recordings
10:24

Electrophysiological and Morphological Characterization of Neuronal Microcircuits in Acute Brain Slices Using Paired Patch-Clamp Recordings

Published on: January 10, 2015

18.0K
Microdissection of Mouse Brain into Functionally and Anatomically Different Regions
08:06

Microdissection of Mouse Brain into Functionally and Anatomically Different Regions

Published on: February 15, 2021

58.0K

Area of Science:

  • Neuroscience
  • Network Science
  • Computational Biology

Background:

  • Neural activity dynamics are influenced by anatomical connectivity.
  • The relationship between structural and functional brain networks is not fully understood.
  • How large-scale functional networks emerge from structural topology requires further investigation.

Purpose of the Study:

  • To investigate the association between spatially extended structural and functional brain networks.
  • To understand how the topology of structural networks gives rise to coherent functional network patterns.
  • To identify reliable combinations of structural and functional subnetworks.

Main Methods:

  • Utilized partial least squares, a multivariate statistical technique.
  • Analyzed the association between large-scale structural and functional networks.
  • Examined patterns of correspondence between anatomical and functional connections.

Main Results:

  • Identified multiple statistically robust patterns linking structural and functional subnetworks.
  • Found that functional relationships often arise from distributed, non-overlapping anatomical connections, not a one-to-one mapping.
  • Observed disproportionate representation of structural connections between high-degree hubs.

Conclusions:

  • Cerebral cortex network organization supports diverse functional network configurations.
  • Functional networks frequently diverge from the underlying anatomical substrate.
  • Structural connections between hubs play a critical role in establishing coherent functional networks.