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Update on diagnosis of acute rheumatic fever: 2015 Jones criteria
1Department of Pediatrics, Division of Pediatric Cardiology, İstanbul University Cerrahpaşa School of Medicine, İstanbul, Turkey.
Abstract:
In the final Jones criteria, different diagnostic criteria were established for the diagnosis of acute rheumatic fever for low risk and moderate-high risk populations. Turkey was found to be compatible with moderate-high risk populations as a result of regional screenings performed in terms of acute rheumatic fever and rheumatic heart disease. The changes in the diagnostic criteria for low-risk populations include subclinical carditis found on echocardiogram as a major criterion in addition to carditis found clinically and a body temperature of 38.5°C and above as a minor criterion. In moderate-high risk populations including Turkey, subclinical carditis found on echocardiogram in addition to clinical carditis is used as a major criterion as a new amendment. In addition, aseptic monoarthritis and polyarthralgia are used as major criteria in addition to migratory arthritis and monoarhtralgia is used as a minor criterion among joint findings. However, differentiation of subclinical carditis from physiological valve regurgitation found in healthy individuals and exclusion of other diseases involving joints when aseptic monoarthritis and polyarthralgia are used as major criteria are very important. In addition, a body temperature of 38°C and above and an erythrocyte sedimentation rate of 30 mm/h and above have been accepted as minor criteria. The diagnostic criteria for the first attack have not been changed; three minor findings have been accepted in presence of previous sterptococcal infection in addition to the old cirteria for recurrent attacks. In the final Jones criteria, it has been recommended that patients who do not fully meet the diagnostic criteria of acute rheumatic fever should be treated as acute rheumatic fever if another diagnosis is not considered and should be followed up with benzathine penicilin prophylaxis for 12 months. It has been decided that these patients be evaluated 12 months later and a decision for continuation or discontinuation of prophylaxis should be made. In countries where the disease is prevalent, it is very important for physicians to make an accurate diagnosis of acute rheumatic fever with their own logic and assessment in addition to the criteria proposed.
Insights
The updated Jones criteria refine acute rheumatic fever diagnosis for low and moderate-high risk groups, incorporating echocardiogram findings and specific joint/fever indicators. Accurate diagnosis remains crucial, especially in prevalent regions.
Area of Science:
- Cardiology
- Rheumatology
- Infectious Diseases
Background:
- The Jones criteria are essential for diagnosing acute rheumatic fever (ARF).
- Previous iterations required updates to reflect varying population risks and diagnostic capabilities.
- Regional variations in ARF and rheumatic heart disease prevalence necessitate tailored diagnostic approaches.
Purpose of the Study:
- To outline the modifications in the final Jones criteria for diagnosing ARF.
- To adapt diagnostic criteria for low-risk and moderate-high risk populations, including Turkey.
- To emphasize the importance of clinical judgment alongside updated criteria.
Main Methods:
- Revision of major and minor criteria for ARF diagnosis.
- Inclusion of subclinical carditis via echocardiogram as a major criterion.
- Introduction of specific fever thresholds and joint symptom classifications for different risk groups.
Main Results:
- Updated criteria for low-risk populations include subclinical carditis (major) and fever ≥38.5°C (minor).
- Moderate-high risk populations (including Turkey) now consider subclinical carditis (major), aseptic monoarthritis/polyarthralgia (major), and specific fever/ESR levels (minor).
- Criteria for recurrent attacks and management of patients not fully meeting criteria have been clarified, recommending prophylaxis and follow-up.
Conclusions:
- The final Jones criteria offer refined diagnostic pathways for ARF based on population risk.
- Accurate differentiation of subclinical carditis and joint conditions is vital for correct diagnosis.
- Physician assessment remains critical for accurate ARF diagnosis and management in endemic areas.
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