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Spontaneous epileptiform discharges in isolated human cortical slices from epileptic patients
1Department of Neurosurgery, Gainesville Veterans Administration Medical Center, FL.
Neuroscience Letters
|March 27, 1989
Abstract:
Human epileptic in vitro brain slices were obtained at ablative neurosurgical procedures and examined for spontaneous extracellular field potentials. Electrical events resembling interictal spikes and seizure discharges were observed in tissue from the electrocorticographic epileptic foci, but not in control tissue. It appears that important differences between the epileptic focus and normal tissue are maintained in vitro.