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Breast Cancer Risk Factors among Ugandan Women at a Tertiary Hospital: A Case-Control Study.
Moses Galukande1, Henry Wabinga, Florence Mirembe
1Department of Surgery, Makerere University College of Health Sciences, Kampala, Uganda.
Oncology
|April 23, 2016
Summary
Breastfeeding appears to significantly lower breast cancer risk in Ugandan women. This study highlights breastfeeding as a protective factor against breast cancer in this population.
Area of Science:
- Oncology
- Epidemiology
- Public Health
Background:
- Breast cancer incidence is rising steeply in sub-Saharan Africa, particularly in Uganda.
- Limited research exists on breast cancer risk factors, including reproductive factors, among Ugandan women.
Purpose of the Study:
- To identify breast cancer risk factors in indigenous Ugandan women.
- To investigate the association between reproductive factors and breast cancer risk.
Main Methods:
- A hospital-based, unmatched case-control study was conducted.
- Structured questionnaires were used for interviews between 2011 and 2012.
- Logistic regression analysis was employed to determine odds ratios (ORs) and 95% confidence intervals (CIs).
Main Results:
- The study included 113 breast cancer cases and 237 controls.
- Breastfeeding was associated with significantly lower odds of breast cancer (adjusted OR = 0.04; 95% CI: 0.01, 0.18).
- No significant association was found for early age at first full-term birth or urban residence.
Conclusions:
- Breastfeeding is a key factor associated with reduced breast cancer risk.
- Further research is needed to explore other reproductive factors and their impact on breast cancer in Ugandan women.
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