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Isolation, Characterization, and Total DNA Extraction to Identify Endophytic Fungi in Mycoheterotrophic Plants

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Pseudofungi: A Diagnostic Pitfall.

Kirill A Lyapichev¹, Apeksha N Agarwal¹, Andrew E Rosenberg¹

¹University of Miami Miller School of Medicine, Miami, FL, USA Jackson, Memorial Hospital, Miami, FL, USA.

International Journal of Surgical Pathology

|April 24, 2016

Summary

Pseudofungi mimic true fungal elements, posing a diagnostic challenge. Accurate identification using histochemical stains is crucial to prevent unnecessary antifungal treatment.

Keywords:

Gamna-Gandy bodies fungal infection pseudofungi

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Area of Science:

Medical Mycology
Histopathology

Background:

Pseudofungi present as septate hyphae-like structures.
Their morphology closely resembles true fungal elements, complicating histopathological diagnosis.

Observation:

A case report details pseudofungi identified within a paratracheal lymph node.
Morphological characteristics of these pseudofungi were meticulously analyzed.

Findings:

Histochemical stains are essential for differentiating pseudofungi from true fungi.
Careful morphologic analysis aids in accurate identification.

Implications:

Distinguishing pseudofungi from fungal infections is vital to avoid inappropriate antifungal therapy.
This distinction ensures correct patient management and resource allocation.