Related Experiment Video
Updated: Mar 22, 2026

Author Spotlight: Advancing Human Brain Modulation – Optimized Protocols for Transcranial Ultrasound Stimulation Experiments
Published on: June 28, 2024
A framework for simulating ultrasound imaging based on first order nonlinear pressure-velocity relations
Yigang Du1, Rui Fan2, Yong Li2
1National-Regional Key Technology Engineering Laboratory for Medical Ultrasound, Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Department of Biomedical Engineering, School of Medicine, Shenzhen University, CN-518060 Shenzhen, China; Shenzhen Mindray Bio-Medical Electronics Co. Ltd., CN-518057 Shenzhen, China; College of Information Engineering, Shenzhen University, CN-518060 Shenzhen, China.
This study introduces a new ultrasound imaging framework using nonlinear pressure-velocity relations (NPVR) to simulate wave propagation and reflections. The framework accurately models linear and nonlinear ultrasound, enabling advanced imaging capabilities.
Area of Science:
- Medical Imaging
- Acoustics
- Computational Physics
Background:
- Ultrasound imaging relies on accurate simulation of wave propagation.
- Modeling nonlinear ultrasound effects is crucial for advanced imaging applications.
- Existing simulation methods have limitations in accuracy and scope.
Purpose of the Study:
- To present a novel ultrasound imaging framework.
- To simulate both linear and nonlinear ultrasound propagation and reflections.
- To validate the framework's accuracy against established methods.
Main Methods:
- Utilized first-order nonlinear pressure-velocity relations (NPVR).
- Implemented a half-time staggered solution and pseudospectral method.
- Simulated 2D and 3D fields with arbitrary initialization parameters.
Main Results:
- Achieved low root mean square (RMS) errors for linear propagation (e.g., 3% with ASA).
- Demonstrated accuracy for nonlinear propagation, with RMS errors comparable to Abersim.
- Showcased error reduction in nonlinear simulations by increasing sampling frequency.
Conclusions:
- The developed NPVR framework accurately simulates linear and nonlinear ultrasound propagation.
- The framework provides a versatile tool for generating simulated ultrasound channel data.
- This approach enhances the potential for high-fidelity ultrasound imaging simulations.
Related Concept Videos
Basic Equation for Pressure Field
Sound as Pressure Waves
The pressure fluctuation depends on the difference in displacements between the successive points in the...
Deriving the Speed of Sound in a Liquid
The speed of sound in fluids can be derived by considering a mechanical wave...
Pressure Variation in a Fluid at Rest
When measuring pressure at two different levels within the fluid, the difference in...
Fluid Pressure over Curved Plate of Constant Width
Steady, Laminar Flow Between Parallel Plates

