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Synthesis of an In vivo MRI-detectable Apoptosis Probe
Published on: July 31, 2012
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In Vivo Apoptosis Imaging Using Site-Specifically (68)Ga-Labeled Annexin V
1Nuclear Medicine, NUTRIM, Maastricht University Medical Center, P Debeyelaan 25, 6229 HX, Maastricht, Netherlands. Matthias.bauwens@mumc.nl.
Methods in Molecular Biology (Clifton, N.J.)
|April 25, 2016
Abstract:
Noninvasive molecular imaging, using positron emission tomography (PET), is an important technique to visualize metabolic processes in vivo. It also allows to visualize the process of apoptosis, by using radiolabeled compounds such as Annexin V, that bind to extracellular phosphatidylserine (PS). This chapter describes the radiosynthesis of (68)Ga-labeled Annexin V and how to noninvasively image apoptosis in vivo.
