Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model01:09

Theories of Dissolution: The Danckwerts' Model and Interfacial Barrier Model

897
Various dissolution theories provide insight into the factors that influence the dissolution rate. Danckwerts' Model suggests that turbulence, rather than a stagnant layer, characterizes the dissolution medium at the solid-liquid interface. In this model, the agitated solvent contains macroscopic packets that move to the interface via eddy currents, facilitating the absorption and delivery of the drug to the bulk solution. The regular replenishment of solvent packets maintains the...
897
Solubility Equilibria: Overview01:09

Solubility Equilibria: Overview

1.8K
When a substance such as sodium chloride is added to water, it dissolves, forming an aqueous solution. The extent of dissolution is called solubility. The process of dissolution can exist in equilibrium, just like other chemical processes. Solubility equilibria are also called precipitation equilibria because the process of solubility can be reversible. The reverse of the solubility process is called precipitation.
Solubility is important in biological and environmental processes. A notable...
1.8K
Factors Affecting Dissolution: Particle Size and Effective Surface Area01:23

Factors Affecting Dissolution: Particle Size and Effective Surface Area

1.9K
Dissolution kinetics, an essential aspect of oral drug delivery, is significantly influenced by the drug's particle size. According to the Noyes-Whitney dissolution model, the dissolution rate correlates directly with the drug's surface area. The larger the surface area, the higher the drug's solubility in water, leading to a faster drug dissolution rate. Reducing particle size increases the effective surface area, enhancing the dissolution process. Micronization and nanosizing are...
1.9K
Theories of Dissolution: Diffusion Layer Model01:15

Theories of Dissolution: Diffusion Layer Model

2.1K
Dissolution, the process by which drug particles dissolve in a solvent, is explained by the diffusion layer model, a theoretical framework that simulates the absorption of oral drugs and allows us to analyze experimental data.
This process starts with a thin layer, saturated with the drug, forming at the interface between the solid and liquid. The solute then diffuses from this layer into the main solution. The Noyes-Whitney equation suggests that the rate of dissolution relies on the diffusion...
2.1K
Hydration of Cement01:24

Hydration of Cement

1.3K
Hydration of cement is a chemical reaction between cement particles and water. This process occurs primarily through two mechanisms: through-solution and topochemical. In the through-solution process, anhydrous compounds dissolve into their constituents, hydrates form in the solution, and then precipitate from the supersaturated solution. The topochemical process involves solid-state reactions at the cement particle surface. The through-solution process dominates the topochemical process at the...
1.3K
Solution Equilibrium and Saturation01:59

Solution Equilibrium and Saturation

22.6K
Imagine adding a small amount of sugar to a glass of water, stirring until all the sugar has dissolved, and then adding a bit more. You can repeat this process until the sugar concentration of the solution reaches its natural limit, a limit determined primarily by the relative strengths of the solute-solute, solute-solvent, and solvent-solvent attractive forces. You can be certain that you have reached this limit because, no matter how long you stir the solution, undissolved sugar remains. The...
22.6K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Theta Oscillations, Oculomotor Processing, and Neural Synchronization: A Review.

Brain sciences·2026
Same author

Genome-wide analysis of biosynthetic gene clusters reveals hidden metabolic diversity in bacterial fish pathogens.

World journal of microbiology & biotechnology·2026
Same author

Machine learning can predict setting behavior and strength evolution of hydrating cement systems.

Journal of the American Ceramic Society. American Ceramic Society·2026
Same author

Metal-Organic Framework Node-Supported Single-Site Iron(III)-Hydroxyl Catalyst for Regioselective Hydroxylation of Arenes.

Inorganic chemistry·2026
Same author

Graphite-Based Electrochemical Degradation of Congo Red in Aqueous Media: An Eco-Sustainable Approach for Treatment of Residual Dye in Wastewater.

Water environment research : a research publication of the Water Environment Federation·2026
Same author

DNA conformational flexibility descriptors improve transcription factor binding prediction across diverse transcription factor families.

Genome research·2026
Same journal

Laser-Assisted Electrochemical Deposition of Bilateral Au Coatings on Ni Foils: Mechanism and Experimental Study.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Mechanistic Insights into Pulmonary Surfactant Inactivation.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

MPN-GE Bilayer Interphase Construction: Green Modification Derived from Biomass and Synergistic Enhancement of CFRP.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Magnetically Retrievable Core@Shell Nanocomposites for Rare Earth Element Adsorption: Experimental and Machine Learning Insights.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Microstreaming of a Pneumatically Controlled Bubble under Hydrostatic Pressure and Crossflow.

Langmuir : the ACS journal of surfaces and colloids·2026
Same journal

Tuning Pore Sizes of Core-Shell Dendritic Mesoporous Silica Nanoparticles for Efficient Loading of Functional Materials.

Langmuir : the ACS journal of surfaces and colloids·2026
See all related articles

Related Experiment Video

Updated: Mar 22, 2026

Preparation of Functional Silica Using a Bioinspired Method
08:04

Preparation of Functional Silica Using a Bioinspired Method

Published on: August 1, 2018

17.9K

Topological Control on Silicates' Dissolution Kinetics.

Isabella Pignatelli1, Aditya Kumar1, Mathieu Bauchy1

  • 1Laboratory for the Chemistry of Construction Materials (LC2), Department of Civil and Environmental Engineering, ‡Physics of AmoRphous and Inorganic Solids Laboratory (PARISlab), Department of Civil and Environmental Engineering, and §California Nanosystems Institute (CNSI), University of California, Los Angeles , Los Angeles, California 90095, United States.

Langmuir : the ACS Journal of Surfaces and Colloids
|April 26, 2016
PubMed
Summary
This summary is machine-generated.

Silicate solids dissolve at varying rates, influenced by their structure. This study links dissolution speed to the number of chemical topological constraints within the solid material.

More Related Videos

Preparation of Macroporous Epitaxial Quartz Films on Silicon by Chemical Solution Deposition
07:37

Preparation of Macroporous Epitaxial Quartz Films on Silicon by Chemical Solution Deposition

Published on: December 21, 2015

9.8K
Fluid-cell Raman Spectroscopy for operando Studies of Reaction and Transport Phenomena during Silicate Glass Corrosion
06:48

Fluid-cell Raman Spectroscopy for operando Studies of Reaction and Transport Phenomena during Silicate Glass Corrosion

Published on: May 9, 2025

1.3K

Related Experiment Videos

Last Updated: Mar 22, 2026

Preparation of Functional Silica Using a Bioinspired Method
08:04

Preparation of Functional Silica Using a Bioinspired Method

Published on: August 1, 2018

17.9K
Preparation of Macroporous Epitaxial Quartz Films on Silicon by Chemical Solution Deposition
07:37

Preparation of Macroporous Epitaxial Quartz Films on Silicon by Chemical Solution Deposition

Published on: December 21, 2015

9.8K
Fluid-cell Raman Spectroscopy for operando Studies of Reaction and Transport Phenomena during Silicate Glass Corrosion
06:48

Fluid-cell Raman Spectroscopy for operando Studies of Reaction and Transport Phenomena during Silicate Glass Corrosion

Published on: May 9, 2025

1.3K

Area of Science:

  • Geochemistry
  • Materials Science
  • Chemical Kinetics

Background:

  • Silicate solids dissolve in water, with rates varying significantly based on composition and structure.
  • Understanding the structural factors controlling silicate dissolution kinetics is crucial but remains incomplete.

Purpose of the Study:

  • To identify key structural descriptors that govern the dissolution rates of silicate glasses and crystals.
  • To establish a correlation between silicate structure and its aqueous dissolution kinetics.

Main Methods:

  • Pioneering dissolution experiments were conducted on various silicate materials.
  • Atomistic simulations were employed to analyze the structural properties of the dissolving solids.
  • Dissolution rates spanning four orders of magnitude were measured and analyzed.

Main Results:

  • A direct correlation was established between silicate dissolution rates and the number of chemical topological constraints.
  • The number of topological constraints was found to indicate the effective activation energy for dissolution.
  • These constraints hinder local network reorganization, impacting the dissolution process.

Conclusions:

  • The number of chemical topological constraints is a critical structural descriptor controlling silicate dissolution rates.
  • This finding provides a new mechanistic understanding of silicate-water interactions.
  • The results offer a predictive capability for silicate dissolution behavior based on structural analysis.