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Updated: Mar 22, 2026

Rapid Evaluation of Toxicity of Chemical Compounds Using Zebrafish Embryos
Published on: August 25, 2019
Zebrafish dives into food research: effectiveness assessment of bioactive compounds
M Caro1, I Iturria, M Martinez-Santos
1AZTI, Food Research, Astondo Bidea 609, 48160 Derio, Spain. virginia.navarros@ehu.eus.
Abstract:
Zebrafish have been traditionally used in ecotoxicology and developmental biology. However, due to the advances in available methodologies and the similitude with mammals, it has been increasingly used in other fields. One of the most recent fields using zebrafish is food research, being the focus of this review. Most relevant and recent publications including food component toxicity and key metabolic effects together with effectiveness on some zebrafish disease models have been reviewed. This model is a good intermediate tool between in vitro and rodent models, because it provides information from a complete organism in a fast and cost-effective manner. Definitely, in the near future, we will see this model being used by the ingredient suppliers and scientists in order to show the potential impact on health of several compounds.

