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[Results of tuberculosis screening in children with household contact]
A Berraies1, B Hamdi1, J Ammar1
1Pavillon B, hôpital Abderrahmen Mami, 2080 Ariana, Tunisie.
Insights
Tuberculosis screening in children after household contact revealed a high contamination rate. Prompt diagnosis in adults is crucial to prevent childhood tuberculosis transmission.
Area of Science:
- Pediatrics
- Infectious Diseases
- Public Health
Background:
- Tuberculosis (TB) screening in children is vital for early detection of latent TB infection.
- Preventing progression from latent infection to active TB disease in pediatric populations is a public health priority.
Purpose of the Study:
- To assess the rate of tuberculosis infection and disease in children with household contact.
- To identify risk factors associated with TB transmission within families.
Main Methods:
- A prospective study conducted between November 2009 and January 2013.
- Involved 83 children presenting to a pediatric department following household exposure to tuberculosis.
- Data collection included demographic information and TB status.
Main Results:
- Latent TB infection was diagnosed in 31.3% of children, with active TB in 10.8%.
- Close daytime contact (68.7%) and shared bedrooms (57.8%) were common.
- Risk factors included diagnostic delay in the index case (>30 days), index case cavitation on chest X-ray, and close daytime contact.
Conclusions:
- Household contact with tuberculosis leads to a significant rate of infection in children.
- Reducing diagnostic delays in adult tuberculosis cases is essential to minimize childhood exposure and infection.
Introduction:
Tuberculosis screening in children is important to identify and treat latent tuberculosis infection and thus avoid progression to disease.
Methods:
It is a prospective study realized in 83 children between November 2009 and January 2013 who consulted after a household contact for tuberculosis in the pediatric department B of Abderrahmen Mami hospital of Ariana.
Results:
The mean age of the children was 4.8 years (3 months-15 years). A latent tuberculosis infection was diagnosed in 31.3% of children, 10.8% had tuberculosis and 57.8% were considered healthy. Fifty-seven children (68.7%) had a close daytime contact with the index and 57.8% slept in the same bedroom of the contaminator. The identified risk factors were the diagnosis delay of the index of more than 30 days (P=0.023), presence of cavitations on the chest X-ray of the index (P=0.029) and a close daytime contact (P=0.004).
Conclusion:
Our study showed a high rate of contamination in children with a household contact. Efforts are needed to shorten the time to diagnosis of adults' tuberculosis.
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