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Updated: Mar 22, 2026
Doppler Optical Coherence Tomography of Retinal Circulation
Published on: September 18, 2012
Biometry with a new swept-source optical coherence tomography biometer: Repeatability and agreement with an optical
Mathew Kurian1, Nikhil Negalur1, Sudeep Das1
1From Narayana Nethralaya, Bangalore, Karnataka, India.
Purpose:
To assess the repeatability of a new swept-source optical coherence tomography (SS-OCT) biometer (IOLMaster 700) and evaluate the agreement with an optical low-coherence reflectometry (OLCR) biometer (Lenstar 900) in cataractous eyes.
Setting:
Tertiary eyecare facility.
Design:
Prospective evaluation of a diagnostic test.
Methods:
Eyes of patients had 3 consecutive scans acquired by the same operator. The repeatability of measurements was assessed using the within-subject standard deviation and coefficient of variation (CoV). Agreement between the mean measurements of each machine was evaluated.
Results:
The study comprised 100 eyes of 100 patients. The median lens thickness and axial length (AL) measurements were significantly greater (P < .001) with SS-OCT (4.29 mm and 23.5 mm, respectively, versus 4.25 mm and 23.4 mm, respectively); anterior chamber depth (ACD) was greater with OLCR (2.72 mm versus 2.70 mm, respectively) (P < .001). The within-subject standard deviation and CoV of the AL (0.01 and 0.05, respectively) and the ACD (0.04 and 1.22, respectively) measurements showed lower variability with SS-OCT (0.05 and 0.21, respectively, for AL; 0.06 and 1.99, respectively, for ACD) than with OLCR. Good agreement was seen for anterior segment measurements between the 2 devices. The 95% limits of agreement of most parameters fell within the test-retest variability of the parameters. The SS-OCT biometer also showed better penetration in dense posterior subcapsular cataracts, measuring AL successfully in 96% of cases.
Conclusions:
The new SS-OCT biometer showed good repeatability and agreement with the OLCR biometer. The SS-OCT biometer measured the AL with fewer dropouts compared with the OLCR even in dense cataracts.
Financial Disclosure:
None of the authors has a financial or proprietary interest in any material or method mentioned.
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