Related Experiment Video
Updated: Mar 22, 2026
High-speed Video Microscopy Analysis for First-line Diagnosis of Primary Ciliary Dyskinesia
Published on: January 19, 2022
Primary ciliary dyskinesia in two English Cocker Spaniels
E T Bell1, P Griffin2, P Martinello2
1Translational Research and Animal Clinical Trial Study (TRACTS) Group, Faculty of Veterinary Science, The University of Melbourne, Parkville, Victoria, Australia. belle@unimelb.edu.au.
Background:
Primary ciliary dyskinesia (PCD) is an inherited condition characterised by structural and functional defects of ciliated cells. Ciliated cells are present in several different anatomic locations and PCD can thus cause a variety of clinical signs; however, the predominant clinical signs in dogs are respiratory in nature, most commonly chronic nasal discharge and recurrent lower respiratory tract infections commencing in the neonatal period.
Case Report And Conclusion:
This report describes two cases of PCD in English Cocker Spaniel puppies presenting with chronic nasal discharge and bronchopneumonia. We describe the use of a minimally invasive technique to collect samples suitable for cilial studies for its diagnosis.
