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Outcome and management in infants with esophageal atresia - A single centre observational study

Felipe Donoso1, Ann-Marie Kassa1, Elisabet Gustafson1

  • 1Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.

Journal of Pediatric Surgery
|April 27, 2016
PubMed

Insights

This study on esophageal atresia (EA) repair in infants found a 94.6% survival rate but high rates of anastomotic strictures. Long-gap EA management requires further investigation for optimal outcomes.

Area of Science:

  • Pediatric Surgery
  • Congenital Anomalies
  • Gastrointestinal Surgery

Background:

  • Esophageal atresia (EA) repair outcomes depend on pediatric surgical center quality.
  • Optimal management strategies for EA remain debated.
  • This study examines EA outcomes and management within a single center.

Purpose of the Study:

  • To investigate the outcomes of esophageal atresia repair.
  • To analyze the management strategies for esophageal atresia.
  • To evaluate results in a single pediatric surgical center.

Main Methods:

  • Retrospective review of medical records for infants with repaired EA (1994-2013).
  • Analysis of survival rates, anastomotic leakage, recurrent fistula, and stricture incidence.
  • Specific evaluation of long-gap EA (LGEA) management and outcomes.

Main Results:

  • 129 infants included; overall survival was 94.6%.
  • Anastomotic leakage occurred in 7.0%, recurrent fistula in 4.6%, and stricture in 53.5%.
  • Long-gap EA showed higher complication rates (23.1% leakage, 69.2% stricture).

Conclusions:

  • Outcomes are comparable to international reports, with low mortality but significant morbidity.
  • Anastomotic strictures and LGEA pose considerable challenges.
  • A multicenter EA registry with long-term follow-up is recommended for establishing best practices.
Abstract

Keywords:
Esophageal atresiaMorbidityOutcomeTracheoesophageal fistula

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