Chemical constituents of Solanum coagulans and their antimicrobial activities
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Updated: Mar 22, 2026

Measuring Volatile and Non-volatile Antifungal Activity of Biocontrol Products
Published on: December 5, 2020
Xu-Jie Qin1, Paul-Keilah Lunga2, Yun-Li Zhao3
1State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Science, Kunming 650201, China; University of Chinese Academy of Science, Beijing 100049, China.
Abstract:
The present study aimed at determining the chemical constituents of Solanum coagulans and their antimicrobial activities. The compounds were isolated by various chromatographic techniques and their structures were elucidated on the basis of extensive spectroscopic analysis, chemical methods, and comparison with reported spectroscopic data. One new phenolic glycoside, methyl salicylate 2-O-β-D-glucopyranosyl-(1→2)-β-D-glucopyranoside (1), together with 12 known compounds (2-13), were isolated from the aerial parts of Solanum coagulans. Compound 1 was a new phenolic glycoside, and 2-6 were isolated from Solanum genus for the first time. The antimicrobial activities of the isolated compounds were also evaluated. Compound 7 showed remarkable antifungal activity against T. mentagrophytes, M. gypseum and E. floccosum with MIC values being 3.13, 1.56 and 3.13 μg·mL(-1), respectively.
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