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Published on: August 22, 2025
Delayed perforation after endoscopic submucosal dissection for early gastric cancer: Clinical features and treatment
Takafumi Yano1, Satoshi Tanabe1, Kenji Ishido1
1Takafumi Yano, Kenji Ishido, Mizutomo Azuma, Takuya Wada, Mizuto Suzuki, Natsuko Kawanishi, Sakiko Yamane, Tohru Sasaki, Chikatoshi Katada, Wasaburo Koizumi, Department of Gastroenterology, Kitasato University School of Medicine, Kanagawa 252-0375, Japan.
Abstract:
Perforation is an important procedural complication of endoscopic submucosal dissection (ESD) for early gastric cancer. Although the incidence of delayed perforation after ESD is low, extreme caution is necessary because many cases require surgical intervention. Among 1984 lesions of early gastric cancer treated in our hospital by ESD in 1588 patients from September 2002 through March 2015, delayed perforation developed in 4 patients (4 lesions, 0.25%). A diagnosis of delayed perforation requires prompt action, including surgical intervention when required.
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