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Related Experiment Videos

Analysis of haemorheological variables--methodology and reference values.

B Sandhagen1

  • 1Department of Clinical Physiology, University Hospital, Uppsala, Sweden.

Upsala Journal of Medical Sciences
|January 1, 1989
PubMed
Summary

This study presents routine methods for analyzing hemorheologic variables like plasma viscosity and erythrocyte aggregation using a single viscometer. These methods provide reliable measurements for whole blood apparent viscosity and erythrocyte fluidity in healthy individuals.

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Area of Science:

  • Hematology
  • Biophysics

Background:

  • Hemmorheologic variables are crucial for understanding blood flow dynamics.
  • Standardized analytical methods are needed for consistent hemorheologic assessments.

Purpose of the Study:

  • To establish routine analytical methods for key hemorheologic variables.
  • To analyze plasma viscosity, whole blood apparent viscosity, erythrocyte aggregation, and erythrocyte fluidity.

Main Methods:

  • Utilized a single instrument: the Low Shear 30 rotational couette viscometer.
  • Proposed routine methods for analyzing multiple hemorheologic parameters.
  • Included erythrocyte volume fraction as an additional measured variable.

Main Results:

  • Established reference ranges for hemorheologic variables in healthy adults.

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  • Mean plasma viscosity: 1.31 +/- 0.07 mPa.s.
  • Mean whole blood apparent viscosity differed between sexes (women: 4.3 +/- 0.4 mPa.s; men: 4.8 +/- 0.3 mPa.s).
  • Conclusions:

    • The proposed methods enable reliable analysis of hemorheologic variables using a single viscometer.
    • The study provides normative data for erythrocyte volume fraction, plasma viscosity, whole blood apparent viscosity, erythrocyte aggregation, and erythrocyte fluidity.
    • These findings support the integration of these measurements into routine clinical and research settings.